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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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3D Bioprinting - Modeling In Vitro Tissues and Organs Using Tissue-Specific Bioinks (Paperback, 1st ed. 2019)
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3D Bioprinting - Modeling In Vitro Tissues and Organs Using Tissue-Specific Bioinks (Paperback, 1st ed. 2019)
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This text advances fundamental knowledge in modeling in vitro
tissues/organs as an alternative to 2D cell culture and animal
testing. Prior to engineering in vitro tissues/organs,the
descriptions of prerequisites (from pre-processing to
post-processing) in modeling in vitro tissues/organs are discussed.
The most prevalent technologies that have been widely used for
establishing the in vitro tissue/organ models are also described,
including transwell, cell spheroids/sheets, organoids, and
microfluidic-based chips. In particular, the authors focus on 3D
bioprinting in vitro tissue/organ models using tissue-specific
bioinks. Several representative bioprinting methods and
conventional bioinks are introduced. As a bioink source,
decellularized extracellular matrix (dECM) are importantly covered,
including decellularization methods, evaluation methods for
demonstrating successful decellularization, and material safety.
Taken together, the authors delineate various application examples
of 3D bioprinted in vitro tissue/organ models especially using dECM
bioinks.
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