With poignant insight and humor, Frank Vertosick Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick s patients and unsparing yet fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain the culmination of decades spent struggling to learn an unforgiving craft illuminates both the mysteries of the mind and the realities of the operating room."

This illustrated colour review covers all aspects of neurology and neurosurgery including: dystonia, tremor, akinetic rigid syndrome (Parkinsonian conditions), infectious diseases, headache, brain tumors, demyelinating disease, epilepsy, neuro-ophthalmology, peripheral neuropathy, clinical neurophysiology, pituitary, coma, neurogenetics, surgical technique, hydrocephalus, AVM/aneurysm, pain and trigeminal neuralgia, head injury, spinal injury, stroke and neuroradiology. The editors and contributing authors all specialise in neurology and/or neurosurgery. The book is aimed at professionals in practice and in training, from hospital based doctors preparing for higher qualifications to established physicians in their continuing professional development. The cases are presented randomly, as in real life and, where appropriate, are superbly illustrated.

New edition of a highly successful illustrated guide to neurology and neurosurgery for medical students and junior doctors. Comprehensive guide to neurology and neurosurgery for medical students and junior doctors - competing books do not cover both areas Graphic approach to the subject - concise text is arranged around clear and memorable line diagrams. Readers find this approach accessible and easy to learn form Clarifies a subject area which students tend to find difficult and forbidding Updated and revised in all areas where there have been developments in understanding of neurological disease and in neurological and neurosurgical management. This revision has also incorporated current guidelines, particularly recommendations from National Institute for Health and Clinical Excellence (NICE).

This new book from leading neurosurgeon and author Gary Kraus is an account of traumatic brain injury (TBI) from the time a brain-injured patient arrives in the emergency department through to the wide range of clinical outcomes of such an injury. Written with the voice of experience, the author examines causation of TBI, the patient’s stay in the neuro-intensive care unit and the many neurological assessments and tests that inform the outcomes that the patient and their families will encounter. A wide range of medical professionals will benefit from Dr Kraus’s acute insights into TBI including Neurosurgical residents, Neurosurgeons with a sub-specialist interest in Neuro-Trauma, Neurologists managing patients with post traumatic brain injury, Neuro-Intensivists, Neuro-Psychologists, Researchers/scientists involved in Clinical trial in traumatic brain injury, and those with a specialist interest in Neuro-rehabilitation.

* easy to understand yet gives all the necessary knowledge to a beginner. * illustrated with over 100 example EEGs * includes Normal EEGs * demonstrates the clinical applications of EEGs in Epilepsies and other Brain Disorders

Deep brain stimulation (DBS) is now a firmly established treatment for movement disorders, and an increasing body of evidence supports DBS in the treatment of other neurological and psychiatric disorders. This essential reference guide outlines a practical approach to the use of this paradigm-shifting therapy and covers key aspects of DBS practice. Chapters describe how to implement a DBS program and select appropriate patients, device programming to achieve optimal symptom control, and long-term management of patients. Thoroughly revised, this third edition includes additional chapters on managing patients with emerging applications of DBS. An entire chapter is dedicated to troubleshooting common problems with the therapy as many 'failures' are preventable and addressable. With contributions from experts in the field, this is a must-have reference guide for any clinician working with DBS patients.

Neuroprotection and Regeneration of the Spinal Cord comprehensively covers the most recent research in the field of spinal cord injury. The first part of this book focuses on the latest animal models and clinically oriented work, providing extensive information on morphological factors and, biomechanical analysis, in addition to the mechanism of functional recovery. The book goes on to provide information on clinical relevance introducing analysis of spinal cord injuries using MRI and PET. Edited by renowned experts in the field, this book will provide clinical physicians, basic researchers, and postgraduate students with valuable insight into the cutting-edge research and progress in the field of spinal cord injury, treatment, and repair.

Sir Victor Horsley (1857-1916) was a brilliant and pioneering neurosurgeon who also shaped the direction of clinical medicine through his work with the British Medical Association, Medical Defence Union, and General Medical Council. Before the nervous system could be imaged, Horsley operated successfully on the brain and spinal cord, and performed palliative procedures on patients dying from brain tumours. Nevertheless, he became a social pariah due to his support for nationalised health insurance, child welfare and women's rights, amongst other causes. In this fascinating biography, leading neurologist Dr Michael J. Aminoff places Horsley's life and work in the context of the society in which he lived and explores his influence on the development of neurosurgery and social policies still in effect. The many underlying themes to the book include the interplay of science and politics, and the responsibility of physicians to themselves and for the welfare of society.

This new edition has been fully revised to provide spine surgeons with the latest advances in their field. Beginning with an overview of surgical anatomy of the spine, the following chapters describe numerous surgical techniques for each section of the spine – cervical, thoracic, and lumbosacral. The text covers both traditional and new procedures, and includes discussion on recent technologies such as disk arthroplasty and minimally invasive techniques. The final section of this comprehensive volume focuses on associated practices including graft harvesting, discography, and cement augmentation. Authored by renowned experts in the field, this guide is enhanced by clinical photographs and diagrams. A list of ‘key points’ summarises the most important aspects in each chapter. Previous edition (9789350903261) published in 2013. Key points Fully revised, new edition presenting latest advances in spinal surgery Covers techniques for each section of the spine Authored by internationally recognised, US-based experts in the field Previous edition (9789350903261) published in 2013

Intracranial injury, caused by a transorbital penetrating object, is a neglected topic in neurosurgery. With few exceptions, only occasional publications, often containing merely case histories, are present in the literature. Through a perusal of the world literature -- for the first time -- the author has collected and combined all available and relevant information, trying to give a thorough description of this rare, but extremely dangerous injury. This book is a major and definitive contribution to neurosurgery, but is also of importance to ophthalmology, neurology, traumatology, neuro-radiology and pediatrics.

This book is a comprehensive, focused resource on intraoperative neurophysiological monitoring (IOM). This rapidly evolving field has created a demand for an up-to-date book such as this that builds on foundational concepts necessary to the practice of IOM in the context of anatomy and physiology. Each chapter is designed to not only inform the reader, but to also test the reader on the information presented - therefore promoting practical, problem-based learning. Surpassing the quality of its successful predecessor, Principles of Neurophysiological Assessment, Mapping, and Monitoring, Second Edition, is positioned to suit the needs of residents and fellows studying for the IOM certificate programs, physicians and anesthesiologists practicing IOM, and neurotechnologists both experienced and in training.

A comprehensive review of the current status of antidepressants - how we arrived at this point in their evolution and where we are going in both the near and the long term. It employs both a scientific and historical approach to accomplish these goals. This volume is intended for practitioners who use antidepressants on a daily basis in their practice as well as for the student and researcher. Each will find that it provides a comprehensive and logical approach to this important group of medications. This book is being published as we mark the end of the first 50 years of the modern antidepressant era.

'A SUPERB ACHIEVEMENT' IAN MCEWAN * * * * * What is it like to be a brain surgeon? How does it feel to hold someone's life in your hands, to cut through the stuff that creates thought, feeling and reason? How do you live with the consequences when it all goes wrong? DO NO HARM offers an unforgettable insight into the highs and lows of a life dedicated to operating on the human brain, in all its exquisite complexity. With astonishing candour and compassion, Henry Marsh reveals the exhilarating drama of surgery, the chaos and confusion of a busy modern hospital, and above all the need for hope when faced with life's most agonising decisions. * * * * * Winner: PEN Ackerley Prize South Bank Sky Arts Award for Literature Shortlisted: Costa Biography Award Duff Cooper Prize Wellcome Book Prize Guardian First Book Award Slightly Foxed Best First Biography Prize Longlisted: Samuel Johnson Prize for Non-Fiction

With an emphasis on the "how and why" of contemporary surgery, Operative Techniques in Surgery, Second Edition, features concise, bulleted text, full-color illustrations, and intraoperative photographs to clarify exactly what to look for and how to proceed. Meticulously edited by Drs. Mary T. Hawn, Aurora D. Pryor, Steven J. Hughes, Michael S. Sabel, Kellie R. Brown and Amy J. Goldberg, this comprehensive, two-volume surgical atlas focuses on the steps of each technique, rapidly directing you to the information you need to choose the right approach for each patient, perform it successfully, and achieve the best possible results. Coverage includes open as well as laparoscopic, robotic, endoscopic, and endovascular procedures in gastrointestinal, thoracic, esophageal, colorectal, hepatobiliary, breast, endocrine, dermatologic, vascular, and trauma surgery New, comprehensive section on trauma surgery, helmed by trauma expert Dr. Amy J. Goldberg New section editors for esophageal and foregut surgery and vascular surgery, Dr. Aurora D. Pryor minimally invasive surgery leader and Kellie R. Brown, expert in vascular surgery. New videos, personally selected by contributing authors and editors, accompany numerous chapters throughout the book Extensive updates throughout, including new coverage of the American Board of Surgery's SCORE Curricula for General Surgery and for Complex General Surgical Oncology Each procedure follows the same format: differential diagnosis, patient history and physical findings, imaging and other diagnostic studies, surgical management, techniques, pearls and pitfalls, postoperative care, outcomes, and complications Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Part of the Neurosurgery by Example series, this volume on pain neurosurgery presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore the spectrum of clinical diversity and complexity within pain neurosurgery, including trigeminal neuralgia, postherpetic neuralgia, occipital neuralgia, percutaneous cordotomy for cancer-associated pain, chronic lumbar radiculopathy, and more. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Pain Neurosurgery is appropriate for neurosurgeons who wish to learn more about a subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

1 Die Chirurgie des Felsenbeins und der lateralen Schadelbasis.- 1 Unsere Langzeiterfahrungen bei der Behandlung von jugulotympanalen Paragangliomen.- 2 Der Wert der Somatostatinszintigraphie in der Diagnostik der Paragangliome.- 3 Das Felsenbeinkarzinom - eine interdisziplinare Herausforderung.- 4 Unser Konzept beim Karzinom des ausseren Gehoerganges.- 5 Moeglichkeiten und Grenzen der Karotiskanalchirurgie.- 6 Intrakraniell bedrohliche Erkrankungen durch unscheinbare Entzundungen des Mittelohrs.- 7 Der transtemporale Zugang zum Klivus und zur petroklivalen Region Chirurgische Anatomie und klinische Erfahrung.- 8 Topographische Anatomie der Felsenbeinspitze und des Dorello-Kanals.- 9 Differentialdiagnosen von Raumforderungen des inneren Gehoergangs.- 10 Zum Stellenwert der Sakkotomierevision in der Behandlung des Morbus Meniere.- 11 Der subtemporale Zugangsweg - eine gehoererhaltende Alternative beim Felsenbeincholesteatom.- 12 Wie stellt sich die laterale Schadelbasis im Dunnschnittplastinat dar?.- 13 Langerhans-Zellhistiozytose mit Beteiligung des Felsenbeins.- 14 Massive Osteolyse Gorham-Stout des Felsenbeins und des kraniozervikalen UEbergangs.- 15 Falldarstellung: Lymphangiom des Felsenbeins.- 16 Missbildungen der lateralen Schadelbasis.- 2 Die Therapie des Vestibularisschwannoms.- 17 Funktionserhaltende Chirurgie des Akustikusneurinoms - Ergebnisse interdisziplinarer Kooperation.- 18 Hoervermoegen vor, wahrend und nach transtemporaler Akustikusneurinomexstirpation.- 19 Wurzburger Schule der Akustikusneurinomchirurgie Interdisziplinare Chirurgie des Akustikusneurinoms - Wurzburger Konzept aus der Sicht des Otochirurgen.- 20 Zur Wait-and-See-Strategie beim einseitigen Akustikusneurinom.- 21 Die radiochirurgische Therapie des Akustikusneurinoms Technik im internationalen Vergleich.- 22 Rundtischgesprach zur Therapie des Vestibularisschwannoms.- 3 "Multi-information-guided therapy", CAS und neue Technologien in der Schadelbasischirurgie.- 23 3D-Navigation an der frontalen und lateralen Schadelbasis.- 24 Intraoperative Bildgebung und Neuronavigation - Gegenwart und Weiterentwicklung.- 25 Die Kombination der konventionellen CAS mit der intraoperativen Navigation der Laterobasis: enhanced CAS.- 26 Telemedizin in der Chirurgie der lateralen Schadelbasis - Vergleich ISDN, Internet, ATM.- 27 Computerassistierte Chirurgie der lateralen Schadelbasis Aktuelle Moeglichkeiten und zukunftige Entwicklungen.- 28 Variationen des navigationsgestutzten Zugangs zur lateralen Schadelbasis.- 29 Moegliche Fehler bei der Anwendung von CAS-Systemen an der Schadelbasis.- 30 Anwendungsmoeglichkeiten der Telemedizin in der Schadelbasischirurgie.- 31 MRT-Visualisierung der Schadelbasisregion von unfixierten und kurzzeitfixierten Materialien.- 4 Experimentelle und histopathologische Untersuchungen zur Chirurgie der lateralen Schadelbasis.- 32 Tierexperimentelle Untersuchung zur medikamentoesen Therapie der traumatischen Optikusneuropathie.- 33 Molekulargenetische und zellbiologische Untersuchungen am NF2-Gen.- 34 Analyse des adenoidzystischen Karzinomes mittels Laser-Scanning-Zytometrie.- 35 Das maligne fibroese Histiozytom der Kieferhoehle.- 36 Das intratemporale Fazialisneurinom: Diagnostik und Therapie.- 37 Neurobiokompatibilitat von Titan, Gold und Silikon in vitro.- 38 Angiosarkomentstehung in Schwannomen des Nervus vagus.- 39 Minimal-invasiv applizierbare Zell- und Gewebetrager fur die Schadelbasischirurgie.- 40 Dehiszenzen des Paries jugularies und Haufigkeit zusatzlicher Knochenkanale der Fossa jugularis.- 5 Aktuelle Aspekte der Chirurgie der vorderen Schadelbasis.- 41 Neue Aspekte zur Therapie des Lagophthalmus.- 42 Invasive Mukozelen der Stirnhoehle - therapeutisches Vorgehen.- 43 Das Osteosarkom der Schadelbasis.- 44 Dorsale und ventrale kraniozervikale Stabilisierung bei progredienter basilarer Impression nach Densresektion bei PCP.- 45 Optikusdekompression bei bewusstlosen Patienten.- 46 Dislokation des

For more than 30 years, the highly regarded Secrets Series (R) has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Spine Secrets Plus, 3rd Edition, by Dr. Vincent J. Devlin, features the Secrets' popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style - making inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series (R) format gives you the most return for your time - succinct, easy to read, engaging, and highly effective. Fully revised and updated throughout, including protocols and guidelines that are continuously evolving and that increasingly dictate best practices. Expanded PLUS format includes extended coverage, a larger format, colorful visual elements, and larger, detailed images and illustrations to provide an overall enhanced learning experience. Remain at the forefront of the nuances of spine surgery and related specialties with updates on new techniques and technologies, as well as changing treatment options and drug information. Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. Zero in on key information with bulleted lists, mnemonics, and practical tips from prominent specialists - all providing a concise overview of important, board-relevant content. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Foundations for Clinical Neurology presents basic principles of neurology in a user-friendly way for practicing neurologists as well residents, fellows, and students. Written in a clear and concise format, this book will perfectly complement the "traditional" neurology textbook. This volume on neurology is divided in to three primary sections. The first section "Practicing Neurology" covers bedside investigation, diagnosis, imaging techniques, and therapeutics; Section 2, "Topics in Neurologic Disease" reviews subjects in neurologic disease that are often overlooked but are very important; and the third section, "Perspectives" provides insight in to how we talk, think, and develop concepts in neurology. With understanding of the evolution of neurologic concepts, the terminology and classifications used by neurologists, and the methodologies used to prove cause of disorder and disease, the practicing neurologist can provide the most effective care. Topics discussed in Foundations for Clinical Neurology include... -Verbal and nonverbal communication, especially during the history-taking portion of a neurologic examination; -How to be effective and avoid common pitfalls in the neurologic exam; -Difficulties in applying diagnostic criteria and formulating diagnoses; and -Advantages of using CT or MRI scanning in various clinical situations.

Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.

This book describes the specific surgical techniques currently employed in patients with intractable epilepsy; it also covers the relevant technical aspects of general neurosurgery. All of the approaches associated with the various foci of epilepsy within the cerebral hemispheres are considered, including temporal and frontal lobectomies and corticectomies, parietal and occipital lobe resections, corpus callosotomy, hemispherectomy, and multiple subpial incisions. In addition, an individual chapter is devoted to electrocortical stimulation and functional localization of the so-called eloquent cortex. The more general topics on which guidance is provided include bipolar coagulation (with coverage of the physical principles, strength of the coagulating current, use of coagulation forceps, the advantages of correct irrigation, and use of cottonoid patties) and all of the measures required during the performance of operations under local anesthesia. The book is designed to meet the need for a practically oriented source of precise information on the operative procedures employed in epilepsy patients and will be of special value for neurosurgical residents and fellows.

In "Revision Sinus Surgery" the world’s most prominent rhinologists illustrate their experience in diagnosing and managing recurrent sinus disease and skull base lesions. Starting with preoperative planning and medical management, these challenging cases are well-illustrated with the relevant surgical techniques. This invaluable resource is designed to prevent complications and improve the outcomes of revision sinus surgeries. Both practicing and in-training otolaryngologists can use this comprehensive volume as an all-in-one source for the evaluation and management of recurrent sinus disease and skull base pathology.

Behavioral neuroscience encompasses the disciplines of neurobiology and psychology to study mechanisms of behavior. This volume provides a contemporary overview of the current state of how ethics informs behavioral neuroscience research. There is dual emphasis on ethical challenges in experimental animal approaches and in clinical and nonclinical research involving human participants.

Volume 13: Pineal, Pituitary, and Spinal Tumors is organized in six sections, for convenience and quick access to critical information. Section I, Types of Tumors includes a chapter on molecular characterization of Embryonal tumors, a chapter on diagnosis of metastatic oligodendroglioma using fine-needle aspiration cytology, one covering intra-arterial chemotherapy of oligodendroglial tumors and another on the role of cyclooxygenase-2 in the development and growth of Schwannomas, and others, closing with a chapter on trigeminal neuralgia with cerebellopontine angle tumors. Section II, Diagnosis, includes two chapters on cell counting in histopathologic slides of tumors. Section III offers three chapters which discuss aspects of intraoperative ultrasonography. Section IV covers brain tumor surgery, and Section V surveys Brain Metastasis. The final section offers a wide-ranging review of General Diseases, with chapters on, among others, Alexander Disease; Lipoma; Transplantation of human umbilical cord blood mononuclear cells in cases of neonatal hypoxic-ischemic brain damage; and a chapter discussing the use of mobile phones and brain cancer risk in children. Like its twelve predecessors in the series, this volume merits distinction for its thorough approach, its roster of 78 distinguished contributors representing 14 different countries and its detailed examination of leading-edge technology and methods.

This book, featuring more than 180 high spatial resolution images obtained with state-of-the-art MDCT and MRI scanners, depicts in superb detail the anatomy of the temporal bone, recognized to be one of the most complex anatomic areas. In order to facilitate identification of individual anatomic structures, the images are presented in the same way in which they emanate from contemporary imaging modalities, namely as consecutive submillimeter sections in standardized slice orientations, with all anatomic landmarks labeled. While various previous publications have addressed the topic of temporal bone anatomy, none has presented complete isotropic submillimeter 3D volume datasets of MDCT or MRI examinations. The Temporal Bone MDCT and MRI Anatomy offers radiologists, head and neck surgeons, neurosurgeons, and anatomists a comprehensive guide to temporal bone sectional anatomy that resembles as closely as possible the way in which it is now routinely reviewed, i.e., on the screens of diagnostic workstations or picture archiving and communication systems (PACS).

This book offers a complete overview on non colorectal non neuroendocrine (NCRNNE) liver metastases and describes in detail the currently available therapies. Each chapter focuses on the treatment of metastases from a particular primary malignancy and also provides valuable information on incidence, natural history and diagnosis. NCRNNE liver metastases are rare entities compared with colorectal and neuroendocrine metastases, for which the treatments are well codified. While more publications have appeared on the topic in recent years, an in-depth study has to date been lacking. Furthermore, most published series are insufficiently comparable as they comprise patients with NCRNNE hepatic metastases from a variety of primary malignancies and consequently overlook differences in tumor behavior, frequency of isolated hepatic metastases, response to neoadjuvant or adjuvant therapy and interval between diagnosis of the primary tumor and the liver metastases. This book, with its more specific approach, will serve not only as an up-to-date guide to diagnosis and treatment but also as a reference on which to base future studies.