This book discusses theories that link functions to specific anatomical brain regions. The best known of these are the Broca and Wernicke regions, and these have become synonyms for the location of productive and receptive language functions respectively. This Broca-Wernicke model has proved to be such a powerful concept that is remains the predominant view in modern clinical practice. What is fascinating, however, is that there is little evidence for this strictly localist view on language functions. Modern neuroscience and numerous clinical observations in individual patients show that language functions are represented in complex and ever-changing neural networks. It is fair to say that the model is wrong, and that Broca's and Wernicke's areas in their classic forms do not exist. This is a fascinating paradox: why do neurologists and neurosurgeons continue to use these iconic language models in everyday decision-making? In this book, the author uses his background as a neurosurgeon and a neuroscientist to provide some answers to this question. The book acquaints clinicians and researchers with the many different aspects of language representation in the brain. It provides a historical overview of functional localisation, as well as insights into the misjudgements that have kept the localist doctrine alive. It creates an awareness of the need to integrate clinical observations and neuroscientific theories if we want to progress further in clinical language research and patient care.

This book is the first comprehensive work summarizing the advances that have been made in the neurosurgical use of navigated transcranial magnetic stimulation (nTMS) over the past ten years. Having increasingly gained acceptance as a presurgical mapping modality in neurosurgery, today it is widely used for preoperative mapping of cortical motor and language function, risk stratification and improving the accuracy of subcortical fiber bundle visualization. This unique work will provide neurosurgeons and neuroscientists who are starting their nTMS program essential and detailed information on the technique and protocols, as well as the current clinical evidence on and limitations of the various applications of nTMS. At the same time, more experienced nTMS users looking for deeper insights into nTMS mapping and treatment in neurosurgery will find clearly structured, accessible information. The book was prepared by an international mix of authors, each of which was chosen for their status as a respected expert on the respective subtopic, as evinced by their landmark publications on nTMS.

In rare cases of stroke in children and youths, a likely cause is the idiopathic disease moyamoya, characterized by the slow and progressive stenosis and occlusion of the internal carotid artery and the arteries of the circle of Willis. A result of these stenoses is the formation of collaterals that are typically small and fragile, and liable to rupture. While there is no cure for moyamoya, a variety of surgical procedures can be performed to reestablish and maintain adequate blood supply to the affected brain areas. The procedures described here include various revascularization techniques and recommended bypasses. Key Features: With contributions from the world's most renowned bypass surgeons Perioperative management and considerations An overall practical approach to this painstaking high-end surgery Detailed criteria for analyzing the situation and choosing the appropriate procedure General principles of bypass surgery, direct and indirect revascularization, and combined revascularization techniques Step-by-step descriptions of these procedures Rescue strategies when repeat surgery is necessary Surgical Techniques in Moyamoya Vasculopathy is an indispensable guide for the experienced neurovascular surgeon. This book includes complimentary access to a digital copy on https://medone.thieme.com.

A high-yield and comprehensive text-and-video resource for managing commonly encountered spinal conditions Spine surgery has experienced several paradigm shifts during the past few decades, with highly complex techniques introduced at an astoundingly rapid pace. In order for new generations of spine surgeons to stay current and thrive in this innovative era of spine surgery, access to diverse multimedia learning tools is imperative. Video Atlas of Spine Surgery by renowned spine surgeon and educator Howard An and Rush University Medical Center colleagues Philip Louie, Bryce Basques, and Gregory Lopez, is a cutting-edge resource for non-operative and operative management of a diverse spectrum of cervical, thoracic, and lumbar spine conditions. Consisting of 19 chapters, the text is streamlined to facilitate learning the most important steps for each procedure. The book begins with discussion of physical exam maneuvers used to accurately diagnose specific spinal pathologies. Subsequent chapters detail extensive spine surgery techniques for managing degenerative cervical and lumbar conditions. The remaining chapters cover spinal cord, cervical, and thoracolumbar injuries; idiopathic, degenerative, and early-onset scoliosis; kyphosis; spondylolisthesis; spinal infections and inflammatory disorders; and thoracic disc disorders. Key Features Concise, bulleted text and consistent chapter outlines feature epidemiology and prevalence, pathogenesis, clinical presentation, image findings, classification, conservative and surgical management, techniques, postoperative care, and more A myriad of meticulous diagrams and illustrations, spinal imaging and photographs, and 50 high-quality spine surgery videos maximize learning Technical pearls, case examples, and board-style orthopaedic surgery questions at the end of each section optimize comprehension and retention of information This remarkable resource is a must-have for orthopaedic and neurosurgery residents and fellows, as well as practicing spine surgeons. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Robust ABNS exam prep and didactic review of the entire spectrum of neurosurgery from A to Z The American Board of Neurological Surgery oral examination has undergone periodic review and revision over the years, with a new format instituted in spring 2017. This review book is specifically geared to the new format. The ABNS oral examination process is relevant, rigorous, and of value to the neurosurgical specialty and the public, ensuring neurosurgeons meet the highest standards of practice. Neurosurgical Review: For Daily Clinical Use and Oral Board Preparation by Vasilios A. Zerris and distinguished contributors is a multimodal and a visually rich prep tool for the ABNS exam. The resource provides a unique approach to studying and melding online didactic materials with audio-enhanced charts. Readers can use the material as a complete online exam prep course with audio, or use the print version as a quick reference guide. Key Features Charts and schematics provide an excellent learning tool and study prep The high yield and easy to memorize format helps readers "visualize" knowledge Audio files enhance the ability to create a mental framework, thereby increasing comprehension and retention of content Cases presented at the end of each chapter focus primarily on core material tested in the general neurosurgery ABNS exam session taken by all candidates irrespective of their declared subspecialty This is an essential textbook for neurosurgical residents, fellows, and practitioners prepping for the ABNS boards. It also serves as a user-friendly refresher of fundamental knowledge all neurosurgeons need to know. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This book provides neurosurgeons and trainees with the latest techniques in spinal surgery. Divided into three sections, each is dedicated to surgical procedures in a key region of the spine - cervical, thoracic and lumbar. Each topic is presented in a step by step process covering anatomy, indications and contraindications, techniques and outcomes. Authored by internationally recognised, Philadelphia-based experts in the field, this invaluable text is enhanced by more than 200 surgical images and illustrations. Key points Practical guide to latest techniques in spinal surgery for neurosurgeons and trainees In depth coverage of procedures for each section of the spine - cervical, thoracic and lumbar Internationally recognised, Philadelphia-based author team Highly illustrated with surgical images and illustrations

This atlas focuses on the imaging and treatment options available for giant intracranial aneurysms since 1990s in the beginning of the so-called modern endovascular era. During this period, there were significant advances made in the therapy of small intracranial aneurysms though the treatment of giant aneurysms continued to pose an insurmountable challenge. At the turn of this century, this grim scenario gradually improved with better understanding of the pathophysiology of giant intracranial aneurysms. This changed scenario in giant intracranial aneurysm therapy has been illustrated with the aid of informative clinical case studies. The clinical presentation of giant aneurysms in adults and children is described as are the merits of different imaging modalities explained and illustrated. Extensive consideration has been given to modern fusion imaging that has improved our insight into the nature of the disease. Endovascular treatment approaches (including illustrative open surgical approaches) and reconstructive and deconstructive strategies are fully documented, with careful attention given to factors that influence management strategies, treatment choice and complications.The atlas will be a valuable reference and practical aid for neuroradiologists, neurosurgeons, neurologists, fellowship trainees, postgraduate & graduate students.

Unique resource from internationally renowned experts details the key role of sagittal spine balance Through evolution, human verticality became associated with a wide range of normal pelvic shapes and associated pelvic incidence angles (PIs). While all types of sagittal alignment generally provide adequate support to young adults, age, stress, and related degeneration can progressively lead to sagittal imbalance and contribute to various spinal pathologies. Sagittal Balance of the Spine by Pierre Roussouly, Joao Luiz Pinheiro-Franco, Hubert Labelle, Martin Gehrchen, and a cadre of esteemed international contributors focuses on the importance of sagittal alignment and spino-pelvic shape identification in clinical practice. Offering the most comprehensive text on sagittal balance to date, this state-of-the-art, richly illustrated book fills a void in the literature, offering clinical pearls throughout seven sections and 24 chapters. Key Highlights The biomechanics of sagittal balance including spine modeling, primary parameters, spinal curves segmentation, and lumbar lordosis classification The role of sagittal balance in low back pain and degeneration, with discussion of spinal orientation and the contact forces theory, spinal degeneration associated with spinopelvic morphotypes, and compensatory mechanisms Comprehensive analysis of the relationship between sagittal imbalance and isthmic lysis spondylolisthesis, degenerative spondylolisthesis, Scheuermann's kyphosis, adolescent idiopathic scoliosis, and adult scoliosis Posterior and anterior treatment approaches - from spinal fixation and spinal fusion - to spinal osteotomy techniques and management of surgical failure This text is essential reading for every neurosurgical and orthopaedic resident, as well as veteran surgeons who evaluate and treat patients with spine conditions. Clinicians will learn why incorporating sagittal balance evaluations into spinal exams is integral to devising more effective treatment strategies and achieving improved outcomes. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This book offers essential guidance on selecting the most appropriate surgical management option for a variety of spinal conditions, including idiopathic problems, and degenerative disease. While the first part of the book discusses the neuroanatomy and biomechanics of the spine, pain mechanisms, and imaging techniques, the second guides the reader through the diagnostic process and treatment selection for disorders of the different regions of the spine, based on the principles of evidence-based medicine. I.e., it clearly explains why a particular technique should be selected for a specific patient on the basis of the available evidence, which is carefully reviewed. The book identifies potential complications and highlights technical pearls, describing newer surgical techniques and illustrating them with the help of images and accompanying videos. Though primarily intended for neurosurgeons, the book will also be of interest to orthopaedic surgeons, specialists in physical medicine, and pain specialists.

Stemming from the ENEA Young Researcher Committee, this didactical book comprehensively discusses all aspects of pituitary adenomas, particularly the practical aspects arising in everyday clinical practice. Offering valuable tips, it serves as a guide for young trainee endocrinologists facing their first cases of pituitary adenomas. It also includes illustrative clinical cases of acromegaly, prolactinomas, Cushing's disease, and TSHomas. In addition, a Questions & Answers section is available online. The mix of fresh enthusiasm and well-established expertise in the field provided by the editors and the committee they belong to make the book both solid and innovative, with an appropriate balance between the traditional knowledge and the most exciting innovations from recent or ongoing research. Written and edited by young researchers active in the field of neuroendocrinology, it is a valuable resource for anyone working or interested in the field.

One-of-kind textbook provides comprehensive tutorial on cranial anatomy with step-by-step text and visuals Dissection in the anatomical laboratory is a mandatory component of training for neurosurgeons. Acquisition of highly technical skills is a long and arduous task, requiring knowledge of complex surgical anatomy and basic steps for single surgical approaches. Unlike dense textbooks, Operative Cranial Neurosurgical Anatomy by Filippo Gagliardi, Cristian Gragnaniello, Pietro Mortini, and Anthony Caputy provides readers with a user-friendly tutorial on cranial approaches, clearly delineated through concise written instructions and serial images. Essential procedural aspects are discussed in 53 chapters, starting with sections on pre-surgical training and planning, patient positioning, and basic techniques. Subsequent sections detail cranial approaches; transpetrosal approaches; endonasal, transoral, and transmaxillary procedures; vascular procedures; and ventricular shunts procedures. Surgical technique fundamentals and basic variants, including surgical anatomy and landmarks, are highlighted in 500 figures and illustrations. Key Features Summaries, graphics, and schematic drawings provide immediate access to salient information to utilize during surgical dissections and for surgical preparation A wide spectrum of cranial procedures covered in 23 chapters - from the precaruncular approach to the medial orbit and central skull base - to surgical anatomy of the petrous bone Diverse endonasal procedures including sublabial, transphenoidal, modified lothrop, odontoidectomy, and endoscopic endonasal transmaxillary Vascular procedures such as middle cerebral artery bypass and internal maxillary artery bypass This reader-friendly handbook is a must-have resource for every neurosurgical resident and an excellent refresher for all neurosurgeons. It will help residents and fellows optimize the time and quality of practical training in the cadaver lab, learn fundamental surgical techniques in cranial neurosurgery, and thoroughly prepare for cranial neurosurgical cases. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Migraine surgery is the only existing treatment option that can lead to a permanent symptomatic improvement. Surgical techniques and advances in the understanding of the underlying mechanisms are evolving rapidly. This book intends to familiarise surgeons with the concept of migraine headaches and explains the surgical deactivation of trigger sites, which consists of much more than the decompression of pericranial nerves. The traditional notion of the brain as the sole origin of migraine is supplanted by a concept where the alteration of afferent signals in conjunction with peripheral and central sensitization can trigger a migraine attack. Migraine surgery targets the crucial role of extracranial tissues in the genesis of migraine which is corroborated by substantial clinical, anatomical and pathophysiological evidence.

Unique case-based reference presents high-yield images and expertise focused on vascular neuroradiology Imaging in Neurovascular Disease: A Case-Based Approach by Waleed Brinjikji and Timo Krings is unique in its approach, detailing diagnostic and interventional neuroradiology cases based on radiologic findings. The book explores the key role vascular imaging can play in treatment decision making, prognostication, and improving the understanding of the pathophysiology of neurovascular diseases. Spread over 11 chapters, this book covers a full spectrum of neurovascular diseases spanning the age continuum, starting with acute ischemic stroke, concluding with spinal vascular disease. All vascular neuroradiology cases follow a consistent format. After a succinct introduction describing the clinical scenario with relevant case images, the authors present key facts about the disease and the integral role of different neurovascular imaging procedures in disease management. Imaging findings are discussed in depth, with insightful clinical pearls on image-guided procedures and tips on managing potential pitfalls. Key Highlights Almost 800 high-quality noninvasive images, such as MR angiography/MR imaging, CT angiography/CT perfusion, with angiography where applicable, elucidate a spectrum of findings Analysis of the imaging appearance of a diverse array of common to rare neurovascular diseases provides diagnostic and treatment insights Each case concludes with the most important points clinicians need to know, high-yield facts about a specific cerebrovascular disease, and suggested readings for further exploration This unique case-based book is essential reading for radiology, neurology and neurosurgery residents. It will greatly benefit neurovascular disease specialists including radiologists, neurosurgeons and neurologists as well as interested in furthering their knowledge on the use of neuroimaging to guide neurointerventional and neurosurgical procedures to treat cerebrovascular disease. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Neurotrauma in Multiple Choice Questions is the FIRST review book to use the multiple-choice question format in neurosurgical trauma. Students of neurosurgery, the resident, the fellow, the younger neurosurgeon preparing for exams or practice, and even the later stage neurosurgeon are the target audience of this book. The information in this work is in accordance with the most up-to-date best practice evidence, with a style that mirrors the format adopted by the majority of local, regional, and international board examinations. The strategy and format of the questions provide a stepwise progression from definition to surgical decision-making, to a comprehensive and concise overview of neurological trauma.

Endovascular intervention - using medication and devices introduced through catheters or microcatheters placed into the blood vessels through a percutaneous approach - has emerged as a relatively new minimally invasive approach to treat cerebrovascular disease and possibly intracranial neoplasms. This textbook provides a comprehensive review of principles pertinent to endovascular treatment of cerebrovascular diseases and intracranial tumors, with a detailed description of techniques for these procedures and periprocedural management strategies. Particular emphasis is placed on expert interpretation of the quality of evidence provided and implications for practice related to endovascular procedures. This will be essential reading for clinicians working in interventional neurology and cardiology, endovascular neurosurgery, vascular surgery and neuroradiology.

This book gathers the proceedings of the 17th International Conference on Intracranial Pressure and Neuromonitoring, held in Leuven, Belgium in September 2019. It provides an overview of the current understanding, underlying research and future perspectives concerning pathophysiology, biophysics, monitoring and management in traumatic and non-traumatic acute brain injury, hydrocephalus and spinal cord injury, including cerebrovascular autoregulation impairment in neurological as well as non-neurological diseases. The peer-reviewed contributions were prepared by specialists in neurosurgery, neurointensive care and neuroanesthesiology, as well as prominent experts from the fields of physiology, clinical and biomedical engineering, mathematics and informatics. The book continues the time-honored tradition of publishing key presentations from the ICP Conferences in order to facilitate their dissemination within the clinical and research community.

Every neurosurgeon as well as many surgeons in other disciplines, including plastic and orthopedic surgeons, may unexpectedly be confronted with an entrapment syndrome or a nerve trauma. With a view to preventing costly transfers to expert clinics, this manual for practitioners offers optimized step-by-step figures illustrating how best to approach every relevant nerve lesion. Clear advice is also provided on differential diagnosis from inflammatory neuropathies, which will assist in avoiding false indications for surgery. This is a true manual for practitioners that offers excellent guidance for all surgeons while in the operating theater.

This book focuses on subarachnoid hemorrhage (SAH), describing in detail the neurophysiology, anatomy, epidemiology, grading, anesthesia management, coiling and interventional treatment of this dangerous disease. Written by leading international experts, it highlights the state-of-the-art techniques for the diagnosis and treatment (non-surgical and surgical) of SAH and the clinical variations. It also examines the reliability of the new techniques versus the standard clinical methods to predict problems related to SAH and its recent diagnosis and management. The book starts with a brief discussion of the epidemiology of SAH, cerebral circulation, anatomy of brain blood vessels and neurophysiology related to this fatal disease. Then, in the following chapters it covers grading of subarachnoid hemorrhage, anesthesia management of SAH, treatment, subarachnoid hemorrhage coiling and radiological intervention. Lastly, it explores surgical treatment of intracranial aneurysms in more detail, and addresses complications, critical care management and headache in SAH, traumatic SAH and prognosis. Featuring numerous images, tables, schema, illustrations and videos, the book is intended for junior and senior anesthesiologists, neuroscientists, intervention radiologists, intensivists and neurosurgeons.

This book provides a complete overview of imaging of normal and diseased temporal bone. After description of indications for imaging and the cross-sectional imaging anatomy of the area, subsequent chapters address the various diseases and conditions that affect the temporal bone and are likely to be encountered regularly in clinical practice. The classic imaging methods are described and discussed in detail, and individual chapters are included on newer techniques such as functional imaging and diffusion-weighted imaging. There is also a strong focus on postoperative imaging. Throughout, imaging findings are documented with the aid of numerous informative, high-quality illustrations. Temporal Bone Imaging, with its straightforward structure based essentially on topography, will prove of immense value in daily practice.

This second edition of Samii's Essentials in Neurosurgery contains revised and updated versions of chapters from the first edition plus contributions on new topics written by leading neurosurgeons who were trained by Professor Madjid Samii in Hannover, Germany. Almost all fields of neurosurgery are covered. The authors follow the traditional principles of Samii's philosophy in the diagnosis and management of various neurosurgical pathologies, while presenting their own personal experiences. The extensively illustrated texts document clearly how cutting-edge technology in neurosurgery is being applied in new approaches and techniques. This book will greatly assist neurosurgeons, ENT surgeons, neuroradiologists, neurologists, and neurophysiotherapists in their everyday practice.

Stereotaxic neurosurgery in rodents is used by a variety of people working at research laboratories (research staff, technicians, students at animal facilities...). The present handbook presents all the steps necessary to complete a stereotaxic neurosurgery protocol in accordance with current animal welfare guidelines. This book will guide surgeons step by step, from anesthesia to the post-surgery recovery procedures, including asepsis of the surgical tools and surgical zone, analgesia, correctly identifying the reference points on the skull and brain targets, etc. In keeping with the current international trends, the authors above all focus on the following points: the consideration of pain and how to best treat it depending on the type of surgery; and ensuring asepsis. This book will serve as an important reference work and valuable guidebook for the scientific community.

An essential backpack-size resource on the treatment of pediatric neurological conditions Pediatric neurosurgery has witnessed considerable technological advances, resulting in more efficacious outcomes for young patients with hydrocephalus, epilepsy, brain tumors, spinal deformities, and a host of other conditions. The art of pediatric neurosurgery is a delicate balancing act—taking into account child and parents and emotional and disease challenges. As such, the management of serious neurological conditions in pediatric patients must encompass the big picture in addition to treating underlying pathologies. Handbook of Pediatric Neurosurgery by George Jallo, Karl Kothbauer, and Violette Recinos covers the full depth and breadth of this uniquely rewarding subspecialty including congenital, developmental, and acquired disorders. The latest information is provided on anatomy, radiological imaging, and principles guiding the surgical and nonsurgical management of a full spectrum of neurological pathologies impacting infants and children. The book is divided into 11 sections and 56 chapters with state-of-the-art procedures, best practices, and clinical pearls from top pediatric neurosurgeons. Key Features Cranial disorders including Chiari malformations, encephaloceles, Dandy-Walker malformation, and craniosynostosis Benign and malignant tumors—from the hypothalamus and optic pathways to the brainstem and spinal column Spinal abnormalities such as spina bifida, tethered cord, and scoliosis Clinical questions and answers at the end of chapters—ideal for self-testing and exam prep Comprehensive and compact, this is the perfect backpack reference for neurosurgery residents and pediatric neurosurgery fellows to carry on rounds. It is also a must-have resource for seasoned pediatric neurosurgeons and all practitioners entrusted with the neurological care of pediatric patients.