Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
|
Your cart is empty |
|||
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
First published in 1943, "Vitamins and Hormones" is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Key features: Expertise of the contributorsCoverage of a vast array of subjectsIn depth current information at the molecular to the clinical levelsThree-dimensional structures in colorElaborate signaling pathways "
"The HDL Handbook: Biological Functions to Clinical
Implications" brings laboratory research in HDL from bench to
bedside in this needed resource for researchers and clinicians
studying cholesterol, lipids, epidemiology, biochemistry, molecular
medicine, and pathophysiology of cardiovascular diseases. In
addition, researchers and clinicians working with an aging
population, corporate researchers, post-doctorates; medical
students and graduate students will find this publication
usefulbecause the scope of coverage includes basic science,
genetics, epidemiology, and treatment of HDL cholesterol as well as
potential targets to modify HDL cholesterol.
This new volume of "Current Topics in Developmental Biology" covers
the area of mechanisms in regeneration. With an international board
of authors, it provides a comprehensive set of reviews covering
such topics as control of growth during regeneration, skeletal
muscle degeneration and regeneration in mammals and flies, and
suppression of regeneration in mammals.
"Cellular Endocrinology in Health and Disease" describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue. Providing content that crosses disciplines, "Cellular
Endocrinology in Health and Disease" details how cellular endocrine
function contributes to system physiology and mediates endocrine
disorders. A methods section proves novel and useful approaches
across research focus that will be attractive to medical students,
residents, and specialists in the field of endocrinology, as well
as to those interested in cellular regulation. Editors Alfredo
Ulloa-Aguirre and P. Michael Conn, experts in molecular and
cellular aspects of endocrinology, deliver contributions carefully
selected for relevance, impact, and clarity of expression from
leading field experts.
This book is a must-have for anyone interested in obesity or the
physiology of white or brown adipose tissues. It contains
state-of-the-art methods from researchers that are world leaders in
this field. Detailed lab protocols range from methods to visualize
adipocytes and adipose tissues in humans and experimental models,
to convert stem cells into white and brown adipocytes in vitro, to
evaluate aspects of adipocyte metabolism, to inducibly knock out
genes in adipose tissues, and to evaluate transcriptional control
of adipogenesis on a global scale. 1) The study of adipose tissue goes hand in hand with our global effort to understand and reverse the epidemic of obesity and associated medical complications. 2) Contributors include leading researchers who have made tremendous contributions to our ability to investigate white and brown adipose tissues. 3) The wide variety of experimental approaches detailed within this volume: including the evaluation of adipose tissue biology at the molecular, biochemical, cellular, tissue, and organismal levels.
The third edition of Physiology and Anatomy for Nurses and Healthcare Practitioners: A homeostatic approach presents homeostasis as a dynamic concept that provides the basis for understanding health and well-being. It recognises how failure to respond to homeostatic disturbances results in imbalances responsible for signs and symptoms of ill-health, and describes how healthcare interventions seek to reverse those imbalances. Accompanied by colour illustrations and a description of related anatomy, the book provides an integrated explanation of body functioning. It discusses the organisation of the human body, main features and processes that must be controlled for health, the organ systems that act as homeostatic regulators, and effectors of homeostatic regulation. It also discusses influences on homeostasis and provides case studies that place examples of ill health and health care into the context of homeostasis. Features of the third edition include: An overview of microbiology and principles of infection management Expanded information on pharmacological principles and actions of the major classes of drugs Expanded discussion on physiological functions in relation to specific pathologies Updates on how the Human Genome project has impacted healthcare Additional case studies to illustrate the healthcare provider's role as an external agent of homeostatic control Photographs of common clinical conditions Access to an accompanying website with supplemental information An essential physiology and anatomy text, this book guides readers through the basic structure and functions of the body systems to more complex issues of clinical disorders and healthcare practice. Coverage includes the cardiovascular, lymphatic, nervous, endocrine, reproductive, and respiratory systems as well as skeletal muscle, embryo development, and circadian rhythms.
"Polyphenols in Human Health and Disease" documents antioxidant
actions of polyphenols in protection of cells and cell organelles,
critical for understanding their health-promoting actions to help
the dietary supplement industry. The book begins by describing the
fundamentals of absorption, metabolism and bioavailability of
polyphenols, as well as the effect of microbes on polyphenol
structure and function and toxicity. It then examines the role of
polyphenols in the treatment of chronic disease, including vascular
and cardiac health, obesity and diabetes therapy, cancer treatment
and prevention, and more.
This special volume of "Progress in Molecular Biology and
Translational Science" focuses on chronobiology. Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field
This new volume of "Methods in Enzymology" continues the legacy
of this premier serial with quality chapters authored by leaders in
the field. This is the third of three volumes on hydrogen peroxide
and cell signaling, and includes chapters on such topics as the
biological chemistry of hydrogen peroxide, reactive oxygen species
in the activation of MAP kinases, and investigating the role of
reactive oxygen species in regulating autophagy.
This new volume of "Methods in Enzymology" continues the legacy
of this premier serial with quality chapters authored by leaders in
the field. This is the second of three volumes on hydrogen peroxide
and cell signaling, and includes chapters on such topics as the
cellular steady-state of H2O2, evaluating peroxiredoxin sensitivity
towards inactivation by peroxide substrates, and peroxiredoxins as
preferential targets in H2O2-induced signaling.
Handbook of Opium: History and Basis of Opioids in Therapeutics traces the history of poppy from its prehistory, its use in Greek and Egyptian medicine through the European Renaissance, and the opioid epidemic of the present day. The book explores the discovery of morphine and its alkaloids, reviews its biosynthetic process, and covers the evolution of synthetic opioids. Further, it reviews the biological effects of opium and the molecular basis of its actions, including future perspectives in clinical applications with therapeutic targets. The book is interspersed with numerous notes on the events and great minds in history and medicine who advocated, analyzed and advanced opium through history. The book is a comprehensive review on opium, covering a breadth of topics, including its history, botany, chemistry, trade, physiology, clinical use and molecular biology, with numerous references, tables, vignettes and illustrations included for additional understanding.
Written and edited by leaders in the field, " Eosinophils in
Health and Disease" provides immunology researchers and students
with a comprehensive overview of current thought and cutting-edge
eosinophil research, providing chapters on basic science,
disease-specific issues, therapeutics, models for study and areas
of emerging importance. Despite an explosion of discovery in this
area over the last decade, this is the onlyup-to-date resource on
eosinophils and eosinophilia exists. This full-color volumeprovides
an essential collection of world class information that is a
must-have for any immunologist s workbench or bookshelf.
Get an inside view of the muscles in action during every stretch you perform "Delavier's Stretching Anatomy" is your guide for increasing flexibility, improving range of motion, toning muscles, and relieving pain and discomfort. The very best stretches for shoulders, chest, arms, torso, back, hips, and legs are all here, and all in the stunning detail that only Frederic Delavier can provide. With over 550 full-color photos and illustrations, you'll go inside more than 130 exercises to see how muscles interact with surrounding joints and skeletal structures and learn how variations, progressions, and sequencing can affect muscle recruitment, the underlying structures, and ultimately the results. "Delavier's Stretching Anatomy" includes 13 proven programs for increasing muscle tone, releasing tension and stress, and optimizing training and performance in 13 sports, including running, cycling, basketball, soccer, golf, and track and field.The former editor in chief of "PowerMag" in France, author and illustrator Frederic Delavier is a journalist for "Le Monde du" "Muscle" and a contributor to "Men's Health Germany "and several other strength publications. His previous publications, "Strength Training Anatomy "and "Women's Strength Training Anatomy, " have sold more than 2 million copies.
In this thematic volume of "Progress in Molecular Biology and
Translational Science, "researchers reflect on recent developments
and research surrounding G protein-coupled receptors. The chapters
cover a large breadth of research, including GPCR role in stem cell
function and pharmacology. Authors explore in-depth research
techniques and applications of GPCR usage, covering theory,
laboratory approaches, and unique qualities that make GPCRs a
crucial tool in microbiological and cancer research. Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field
This new volume of "Methods in Enzymology" continues the legacy of
this premier serial by containing quality chapters authored by
leaders in the field. This volume coversG protein
coupledreceptorsandincludes chapterson such topics as G
protein-coupled receptor trafficking motifs, structure-based
virtual screening, and automation-friendly high throughput assays
for identification of pharmacoperone drugs.
This new volume of "Methods in Enzymology" continues the legacy
of this premier serial by containing quality chapters authored by
leaders in the field. This volume covers G protein coupled
receptors and includes chapters on such topics as post-translation
modification of GPCR in relationship to biased agonism,
structure-based virtual screening, and GPCR oligomerization in the
brain.
Obesity is an epidemic with enormous health, economic and social
burdens. Current drugs for obesity treatment are far from ideal in
terms of efficacy and side effects. Reviews in this volume of
Progress in Molecular Biology and Translational Science summarize
current status in studies of a number of G protein-coupled
receptors that were shown to be promising targets for obesity
treatments. Some of these receptors also cause monogenic obesity in
humans. Chapters are written by leading experts.
This book focuses on the nutrients and nutraceuticals that promote active and healthy ageing - recently defined by the WHO as the process of development and maintenance of functional capacity that allows well-being at an advanced stage of life. There has been a rapid rise in the use of nutritional interventions as well as specific nutraceuticals in the management of multifactorial aspects of clinical health outcomes. Written by leading experts this book comprehensively discusses the various ageing phenotypes and age-related diseases. It also assesses the nutritional status of the elderly and the various epidemiological factors that influence it. It reviews the role of dietary fiber in disease-free and fully functional ageing. Further, the book explores the benefits of polyphenols, which are secondary plant metabolites, in protecting against cancer, cardiovascular diseases, and various neurodegenerative diseases.
This detailed new edition aims to provide a range of methods and protocols for studying vascular morphogenesis in vivo and in vitro to reflect up-to-date advances in the field. Of note, the book explores endothelial cell signaling is currently understood to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation, and postnatal tissue remodeling. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Vascular Morphogenesis: Methods and Protocols, Second Edition will serve as an ideal guide to this area of study for a broad audience amongst cell biologists, anatomists, pathologists, and physiologists.
This special volume of Progress in Molecular Biology and
Translational Science focuses on the genetics of stem cells. Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field
"Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior" explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes, which direct neurodevelopmental sequence. Are people free to make choices, or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. Author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures, a combination of factors that we choose and do not choose. Written in an authoritative yet accessible style, the book
includes practical descriptions of the function of DNA, discusses
the scientific and historical bases of genethics, and introduces
topics of epigenetics and the predictive power of behavioral
genetics.
This volume explores some of the most exciting recent advances in
basic research on protein phosphorylation in health and disease and
how this knowledge is leading to advances in the various fields.
Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field
This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies.
The gene's eye view of life, proposed in Richard Dawkins acclaimed
bestseller The Selfish Gene, sees living bodies as mere vehicles
for the replication of genetic codes. But in The Music of Life,
world renowned physiologist Denis Noble argues that, to truly
understand life, we must look beyond the "selfish gene" to consider
life on a much wider variety of levels.
"Cellular Physiology of Nerve and Muscle" offers a state of the art introduction to the basic physical, electrical, and chemical principles central to the function of nerve and muscle cells. The text begins with an overview of the origin of electrical membrane potential, then clearly illustrates the cellular physiology of nerve cells and muscle cells. Throughout, this new edition simplifies difficult concepts with accessible models and straightforward descriptions of experimental results. The fourth edition of Cellular Physiology of Nerve and Muscle features new material including: - An all-new introduction to electrical signaling in the nervous
system |
You may like...
Eureka: Biochemistry & Metabolism
Andrew Davison, Anna Milan, …
Paperback
Human - The Science Behind What Makes…
Michael S Gazzaniga
Paperback
Principles Of Anatomy And Physiology…
Gerard J. Tortora, Bryan H. Derrickson
Paperback
R1,841
Discovery Miles 18 410
|