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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
The previous two editions of the "Human Nervous System "have
been the standard reference for the anatomy of the central and
peripheral nervous system of the human. The work has attracted
nearly 2,000 citations, demonstrating that it has a major influence
in the field of neuroscience. The 3e is a complete and updated
revision, with newchapters covering genes and anatomy, gene
expression studies, and glia cells. The book continues to be an
excellent companion to the "Atlas of the Human Brain," and a common
nomenclature throughout the book is enforced. Physiological data,
functional concepts, and correlates to the neuroanatomy of the
major model systems (rat and mouse) as well as brain function round
out the new edition.
This volume explores some of the most exciting recent advances in
basic research on cellular RNA interference mechanisms and how this
knowledge is leading to advances in the various fields.
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of "Methods in Ezymology" is split into 2 parts and comprehensively covers the subject.
In a clear and accessible presentation, Occupational Physiology focuses on important issues in the modern working world. Exploring major public health problems-such as musculoskeletal disorders and stress-this book explains connections between work, well-being, and health based on up-to-date research in the field. It provides useful methods for risk assessment and guidelines on arranging a good working life from the perspective of the working individual, the company, and society as a whole. The book focuses on common, stressful situations in different professions. Reviewing bodily demands and reactions in eight selected common, but contrasting job types, the book explains relevant physiology in a novel way. Rather than being structured according to organs in the body, the book accepts the complex physiology of typical jobs and uses this as an entry. In addition to physiological facts, the book discusses risk factors for disorders and gives ideas on how to organize and design work and tasks so as to optimize health, work ability, and productivity. Although many books cover physiology, they are based on a traditional anatomical structure (e.g., addressing the physiology of the cardiovascular system, the gastrointestinal system, and so forth) and require readers to synthesize this knowledge into real-life complex applications. Occupational Physiology is, instead, structured around a number of typical jobs and explains their physiologies, as complex as they may be. This approach, while still presenting the physiology needed to understand occupational life, demonstrates how to use this information in situations encountered in practice.
Strength and Conditioning: A Concise Introduction offers a concise but comprehensive overview of training for athletic performance. Introducing essential theory and practical techniques in all of the core areas of athletic training, the book clearly demonstrates how to apply fundamental principles in putting together effective real-world training programs. This book encourages students and professionals to think critically about their work and to adopt an evidence-based approach. It explains the inter-dependence of aspects of training such as needs analysis, assessment, injury, competition level, athlete age, and program design, and it fully explains how those aspects should be integrated. Strength and Conditioning is an accessible, engaging, and reflective introduction to the theory and application of strength and conditioning programs. Including clear step-by-step guidance, suggestions for further reading, and detailed sport-specific examples, this is the perfect primer for any strength and conditioning course or for any professional trainer or coach looking to refresh their professional practice. Included in the second edition are in-depth descriptions of free weights, kettlebells, heavy ropes, speed, agility, horizontal force production training, as well as updated research from the strength and conditioning field. Programming chapters and real-world programs provide examples of how to incorporate all the modern strength and conditioning tools. This is the perfect primer for any strength and conditioning course or for any professional trainer or coach looking to refresh their professional practice.
This issue of Endocrinology and Metabolism Clinics will cover Pediatric Endocrinology. Curated by Dr. Andrea Kelly, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Endocrine Sequelae in Childhood Cancer Survivors, Bone Health in Childhood Chronic Disease, Advances in Bone Health Assessment, Inhaled Glucocorticoids and Endocrine Outcomes, Atypical DM (mitochondrial, transplant, CFRD, monogenic), Pediatric Thyroid Cancer (outcomes, genetics, therapeutics), New Technologies in Type 1 diabetes (bionic pancreas, insulin, mobile health), Precocious and Delayed Puberty-Genetic Underpinnings and treatments (various GNRH formulations, implant), Pediatric Type 2 diabetes, Adolescent health outcomes in relation to phthalates.
First published in 1943, "Vitamins and Hormones" is the
longest-running serial published by Academic Press. The Editorial
Board now reflects expertise in the field of hormone action,
vitamin action, X-ray crystal structure, physiology, and enzyme
mechanisms.
Notch signaling is an evolutionarily conserved pathway in
multicellular organisms that regulates cell-fate determination
during development and in stem cells. This volume, which is part of
the Current Topics in Developmental Biology series, covers topics
such as Notch signaling in cardiac development and disease and
Notch in stem cells. International authors provide researchers with
an overview and synthesis of the latest research findings and
contemporary thought in the area.
First published in 1943, "Vitamins and Hormones" is the
longest-running serial published by Academic Press. The Editorial
Board now reflects expertise in the field of hormone action,
vitamin action, X-ray crystal structure, physiology, and enzyme
mechanisms.
Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki's book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book.
Hyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process. Hyaluronic Acid: Production, Properties, Application in Biology and Medicine consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 describes the methods to manufacture and purify hyaluronic acid, including the analytical means for assessing quality of the finished product. Chapter 4 discusses the structure and rheological properties of hyaluronic acid considering effects on conformation and biological properties related to molecular weight. In Chapter 5, the physical and chemical methods for modifying the structure of hyaluronan are discussed including cross-linking using bi-functional reagents, solid-phase modification and effects of the combined action of high pressures and shift deformation. The final chapter focuses on the products derived from hyaluronic acid, including therapeutics composed of modified hyaluronan conjugated to vitamins, amino acids and oligo-peptides. The biological roles and medical applications of this polysaccharide have been extensively studied and this book provides a wealth of scientific data demonstrating the critical role of hyaluronic acid and its promise as a multifaceted bio-macromolecule. Approaching hyaluronic acid from multiple angles, this book links relationships between its biological functions, structure and physical chemical properties. It will be an invaluable resource to researchers, both industrial and academic, involved in all aspects of hyaluronan-based technologies.
This volume, along with its companion (volume 475), presents
methods and protocols dealing with thiol oxidation-reduction
reactions and their implications as they relate tocell signaling.
This firstinstallment of Cadenas and Packer's two-volume treatment
specifically deals with glutathionylation and dethiolation, and
peroxide removal by peroxiredoxins/thioredoxins and glutathione
peroxidases. The critically acclaimed laboratory standard for40
years, "Methods in Enzymology" is one of the most highly respected
publications in the field of biochemistry. Since 1955, each volume
has been eagerly awaited, frequently consulted, and praised by
researchers and reviewers alike.Over 450volumes have been published
to date, and much of the material is relevant even today--truly an
essential publication for researchers in all fields of life
sciences.
Since its first publication in 1989, Anatomy and Human Movement has grown to become a best-selling seminal textbook, helping students to understand and remember the mechanisms which allow movement to take place. Written specifically for physiotherapists and occupational therapists, this textbook is the ideal resource for students learning how to perform a musculoskeletal examination and for practising clinicians who need to refresh their functional anatomy. The approach used is the same as in the previous edition, which shows the physiotherapist's perspective during patient examinations through an intact skin: bones are presented first, followed by accurate descriptions of muscles, joints, nervous system and blood supply. New to this edition, the introduction of an e-learning course as a helpful study aid and an ideal complement to the text. Fully revised and updated text and introduction of online resources Excellent new full-colour images and photographs provide the highest level of clarity Summary boxes for quick reference and overview Detailed and focused account of anatomy for physiotherapists and other allied health professionals Part of the Elsevier Physiotherapy Essentials series, which are key textbooks for students and lecturers
First published in 1943, "Vitamins and Hormones" is the
longest-running serial published by Academic Press. The Editorial
Board now reflects expertise in the field of hormone action,
vitamin action, X-ray crystal structure, physiology, and enzyme
mechanisms.
In this issue of Endocrinology and Metabolism Clinics, guest editors Channa Jayasena and Shalender Bhasin bring their considerable expertise to the topic of Hypogonadism. Provides in-depth reviews on the latest in Hypogonadism. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
G protein-coupled receptors (GPCRs) transduce signals from a
diverse array of endogenous ligands, including ions, amino acids,
nucleotides, lipids, peptides, and large glycoprotein hormones.
They are also responsible for our sensing of exogenous stimuli,
including photons and odorants. GPCRs regulate almost every aspect
of our physiological functions. It is estimated that 40% to 50% of
currently used therapeutic drugs target GPCRs directly or
indirectly. Because the current drugs target only a small portion
of the GPCRs, opportunities for targeting the remaining GPCRs is
enormous. This volume reviews the latest developments in this
rapidly advancing field. * This series provides a forum for discussion of new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields
"Progress in Molecular Biology and Translational Science"
provides a forum for discussion of new discoveries, approaches, and
ideas in molecular biology and translational science. It contains
contributions from leaders in their fields and abundant references.
This volume focuses on translational control in health and
disease. * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields
Adolescent Psychosis: Clinical and Scientific Perspectives discusses new methodologies and novel scientific findings, with a comprehensive orientation into phenomenology, nosology, diagnostics and the history of adolescent early-onset psychosis research. This volume informs on psychotic disorders in adults and discusses recent epidemiological studies, along with co-morbid aspects associated with other neurodevelopmental syndromes and somatic diseases. The book also provides suggestions for future research to bridge neuroscience and the clinic using a translational perspective, from the clinic to the genes and relevant phenotypes, biomarkers, etiological aspects and clinical outcome. Topics discussed bring together expert researchers in the field to represent different translational perspectives and future possibilities.
Close your eyes and ask yourself, 'what do I feel?' You might feel thirsty or tired. You might feel healthy and well or perhaps a little under the weather. Maybe you can feel that you are standing or that you are leaning over. You may also feel the world around you - the shape and texture of an apple in your hand, the feel of a chair you're sitting on. All these feelings have something in common, say psychologists and neuroscientists. They are all mental events, things that happen in the mind. But what if this is all wrong? What if it's not just the mind, but also the body itself that feels? And not merely physical sensations, but other feelings that seem to have nothing to do with bodies. Things like 'emotions' and 'intuitions' - joy or rage, anxiety or optimism, or the feeling of being hard done by or misunderstood? Drawing on the latest research and a range of classic and contemporary thought, How You Feel shows you that your brain and your body are two parts of a single system that creates your mind and mental life. You will discover that you don't have feelings, thoughts and emotions inside your body, you have them with your body. There can be no mind without the body. Psychology is no longer about the brain, or about 'mind and body', it is about the whole that is you.
The Textbook of Nephro-Endocrinology is the definitive
translational reference in the field of nephro-endocrinology,
investigating both the endocrine functions of the kidneys and how
the kidney acts as a target for hormones from other organ systems.
It offers both researchers and clinicians expert, gold-standard
analysis of nephro-endocrine research and translation into the
treatment of diseases such as anemia, chronic kidney disease (CKD),
rickets, osteoprosis, and, hypoparathyroidism.
This book focuses on the life and work of Nathan Zuntz (1847-1920),
a German physiologist, who made significant contributions to high
altitude physiology and aviation medicine.
Understanding how angiogenesis "works" and how to control it will
have massive implications on the management, treatments, and
ultimately the prevention of many common (and not so common)
diseases. Angiogenesis is the growth of new blood vessels and is an
important natural process in the body. A healthy body maintains a
perfect balance of angiogenesis modulators. In many serious disease
states, however, the body loses control over angiogenesis. Diseases
that are angiogenesis-dependent result when blood vessels either
grow excessively or insufficiently.
First published in 1943, "Vitamins and Hormones" is the
longest-running serial published by Academic Press. In the early
days of the serial, the subjects of vitamins and hormones were
quite distinct. The Editorial Board now reflects expertise in the
field of hormone action, vitamin action, X-ray crystal structure,
physiology, and enzyme mechanisms.
Angiogenesis is the growth of new blood vessels and is an important
natural process in the body. A healthy body maintains a perfect
balance of angiogenesis modulators. In many serious disease states,
however, the body loses control over angiogenesis. Diseases that
are angiogenesis-dependent result when blood vessels either grow
excessively or insufficiently. Understanding how angiogenesis
"works" and how to control it, will have massive implications on
the management, treatments, and ultimately the prevention of many
common (and not so common) diseases.
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