As the worldwide prevalence of morbid obesity among adolescents continues to rise, recent years have seen a large increase in the performance of adolescent bariatric surgery. While surgical intervention often becomes necessary when conservative weight-loss therapies have failed, no standards regarding the post-operative regimen and long-term management of adolescent patients have been established. Thus, the treatment of obesity and its co-morbidities requires a multidisciplinary approach, taking into account epidemiological, clinical, nutritional, and genetic aspects of morbid obesity in the pediatric age group. This volume discusses both conventional therapy and surgical options for morbid obesity in the pediatric age group. In the first part, obesity-related diseases, genetics, and psychological factors are analyzed. The second part focuses on current bariatric surgery procedures, including dietary restrictions and guidelines to prevent nutritional deficiencies common after surgery. Therefore, the book will prove an invaluable resource for pediatricians, surgeons, nutritionists, dieticians, and all other health professionals who treat adolescent obesity.

This book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals. But hormones can be found not only in vertebrates, but also in insects, shellfish, spiders, mollusks, even at the origin of metazoan diversification and exhibit the same pathways of synthesis. The book addresses the different classes of hormones: protein/peptides hormones, steroids and juvenile hormones and hormones like catecholamines, thyroid hormones and melatonin. It also discusses the types of hormone receptors, the majority of which are heptahelical G-protein coupled receptors or nuclear receptors. Particular attention is paid to the organs where hormones are created, with specifics on hormonal production and release, while a dedicated chapter details hormonal regulation from very simple to highly complex schemes. The remarkable kinetics of hormones production are also shown, before the book is rounded out by chapters on evolution in the endocrine system, the genetics of endocrine diseases and doping.

Science and Football VIII showcases the very latest scientific research into the variety of sports known as 'football'. These include soccer, the national codes (American football, Australian rules football and Gaelic football), and the rugby codes (union and league). Bridging the gap between theory and practice, this book is by far the most comprehensive collection of current research into football, presenting important new work in key areas such as: physiology of training performance analysis fitness assessment nutrition biomechanics injury and rehabilitation youth football environmental physiology psychology in football sociological perspectives in football Science and Football VIII is an essential resource for all sport scientists, trainers, coaches, physical therapists, physicians, psychologists, educational officers and professionals working across the football codes. Chapter 6 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781138947061_oachapter6.pdf

Physical Activity and the Abdominal Viscera is the first book to examine the response of the visceral organs to acute and chronic physical activity, in cases of both health and disease. Bringing together a previously disparate body of research, Professor Roy Shephard sets out the physiology, function during exercise, pathology of disease, and role of physical activity in preventing and managing disease in the visceral organs. Working systematically through the viscera, the book first identifies the response to exercise and pathologies of the liver, gall bladder and biliary tract, then goes on to examine the function of the kidneys and bladder, and finally covers issues including the spleen, sickle cell disease and prostate cancer. Providing a clear and well-structured guide to the relationship between the visceral organs and physical activity, Physical Activity and the Abdominal Viscera is a vital reference text for academics and upper-level students in sports medicine and clinical exercise physiology, and for health professionals in preventive medicine.

The organs of the gastro-intestinal tract play an essential role in sustained physical activity, but their consideration in exercise-related literature has, to this point, been limited. Physical Activity and the Gastro-Intestinal Tract is the first book to explain the function and response to exercise of the gastro-intestinal system, in cases of both health and disease, and helps to shed light on the role they play in acute and chronic exercise. Professor Roy Shephard synthesises previously disparate research to explain the physiology, function, pathology of disease and role of exercise in both health and chronic disease, covering topics including: physical activity and the oesophagus gastro-duodenal function and physical activity physical activity and peptic ulcers physical activity and gastro-oesophageal cancers physical activity and the function of the large bowel physical activity and chronic intestinal inflammation. With each chapter including a thorough bibliography and signposts to further reading, Physical Activity and the Gastro-Intestinal Tract provides a complete reference for understanding how exercise affects the function of the digestive organs. It is an important text for academics and upper-level students in sports medicine and exercise physiology, and for health professionals in preventative medicine.

Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. "High Altitude: Human Adaptation to Hypoxia "addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high altitudes are covered and chapters discuss these effects on a wide range of diseases. Expert authors provide insight into the care of patients with pre-existing medical conditions that fail in some cases to adapt as well as offer insights into how high altitude research can help critically ill patients. "High Altitude: Human Adaptation to Hypoxia" is an important new volume that offers a window into greater understanding and more successful treatment of hypoxic human diseases."

The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.

In sport disciplines such as running, ice skating, bicycling and cross-country skiing the aerodynamic drag force constitutes the major obstacle to overcome. Furthermore, in ski jumping and in various activities involving a ball the aerodynamic lift force comes in addition into action.

This book describes the various sport disciplines on the basis of aerodynamic analysis and also cover the biomechanics part by illustrative performance examples. Such treatment of the underlying physical phenomena of sport activities gives a valuable supplement to existing literature on sport. The reader will also be guided to references which exist for the various topics discussed, so she or he can go into a deeper study of the particular sport activity at wish.

Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal." Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell's nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging related disorders.

This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world's population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.

Ecophysiology attempts to clarify the role and importance of physiological processes in the ecological relations of species in their natural habitats. Including blood collection and the measurement of plasma components and hormone levels, the basic principles and methods relevant to any ecophysiological study are covered in this text. Examples are collected from a wide range of vertebrates living in deserts, cold climates and oceans. The book is an introduction to ecophysiology for advanced students, as well as researchers in ecology, biodiversity and conservation.

Discover everything you need to know about biology, with the simplest most visual guide to the science of life. How do vaccines work? What is special about stem cells? How did we evolve from bacteria? The science of life can be dauntingly complex, and it can be hard to separate "good" science from "bad", fundamental truths from the much-hyped breakthroughs reported in the media. With clear, easy-to-understand graphics and packed with fascinating facts, How Biology Works demystifies both the core biology that may have eluded us at school, and the cutting-edge life science that makes the news, answering the questions that spark our curiosity. With power to every page, this striking science book: - Is illustrated entirely by specially commissioned, boldly coloured, distinctive, flat, vector graphics that explain each topic clearly and engagingly. - Supports the curriculum up to GCSE, but also includes some higher-level topics and cutting-edge biology that makes the news. - Uses clear, distinctive, eye-catching graphics to make even complex biology easy to understand. -Offers a practical, no-nonsense approach to each subject. Building from life's fundamental ingredients, such as carbon and water, the book explains chemical processes in living cells, controlled by the ultimate biochemical, DNA. It shows how DNA is made of units called genes, which are shuffled in each generation of offspring, leading to variation and evolution. It covers topics from school biology, such as how plants work and how animals, including humans, work, and goes on to ecology and biotechnology. Beyond school science, however, it covers the background to the latest medical technology and biotechnology: how gene therapy works, what stem-cell research is achieving, and how our immune systems, boosted by vaccines, are in an arms race with ever-mutating viruses and other pathogens. At DK, we believe in the power of discovery. So why stop there? How Biology Works is part of DK's widely successful How Stuff Works series. Discover the inner workings of the mind with How the Brain Works, succeed in all things science with How Science Works and discover the cosmos like you've never known before with How Space Works. Whatever topic sparks your interests, there's a plethora of knowledge to discover!

Lipobiology is a rapidly evolving interdisciplinary field which incorporates critical aspects of lipid and lipoprotein chemistry into the disciplines of cell biology and physiology. This series focuses on salient aspects of the role of lipids in metabolic regulation and cellular activation.

From its early beginnings in the 1960s, the academic field of biochemistry of exercise has expanded beyond examining and describing metabolic responses to exercise and adaptations to training to include a wide understanding of molecular biology, cell signalling, interorgan communication, stem cell physiology, and a host of other cellular and biochemical mechanisms regulating acute responses and chronic adaptations related to exercise performance, human health/disease, nutrition, and cellular functioning. The Routledge Handbook on Biochemistry of Exercise is the first book to pull together the full depth and breadth of this subject and to update a rapidly expanding field of study with current issues and controversies and a look forward to future research directions. Bringing together many experts and leading scientists, the book emphasizes the current understanding of the underlying metabolic, cellular, genetic, and cell signalling mechanisms associated with physical activity, exercise, training, and athletic performance as they relate to, interact with, and regulate cellular and muscular adaptations and consequent effects on human health/disease, nutrition and weight control, and human performance. With more emphasis than ever on the need to be physically active and the role that being active plays in our overall health from a whole-body level down to the cell, this book makes an important contribution for scholars, medical practitioners, nutritionists, and coaches/trainers working in research and with a wide range of clients. This text is important reading for all students, scholars, and others with an interest in health, nutrition, and exercise/training in general.

Fatigue is a condition spanning the breadth of human functioning in health and disease and is a central concern in sport and exercise. Even so we are yet to fully understand its causes. One reason for this lack of understanding is that we seldom consider fatigue from an evolutionary perspective - as an adaptation that provided reproductive success. This ground-breaking book outlines the evidence that fatigue is a result of adaptations distinctive to humans. It argues that humans developed adaptations which led to enhanced fatigue resistance compared with other mammals and discusses the implications in the context of exercise, health and performance. Highly illustrated throughout, it covers topics such as defining and measuring fatigue, the emotional aspect of fatigue, how thermoregulation affects the human capacity to resist fatigue, and fatigue in disease. Human Fatigue is essential reading for all exercise scientists as well as graduate and undergraduate students in the broad field of physiology and exercise physiology.

This book on the metabolic aspects of polycystic ovary syndrome (PCOS) reviews the scientific evidence for the key etiological role of insulin resistance in the pathogenesis of PCOS. It also presents a new clinical and diagnostic approach and clearly explains the value of insulin-sensitizing agents, or "insulin sensitizers," in reducing hyperandrogenism and improving fertility outcome. Detailed information is provided on the use of insulin sensitizers such as metformin and inositol and suitable therapeutic protocols are described. All too often, PCOS is treated by gynecologists only as an endocrine disorder, without recognition of the very important part that insulin plays in the syndrome. Practitioners will find this book to be a valuable source of information on PCOS as a metabolic syndrome and a comprehensive guide to achieving good treatment results.

The essentials of medical terminology for the short, self-paced, or online course Medical Terminology Express + Medical Language Lab work together to create an immersive, multimedia experience for students and complete teaching materials for instructors that are perfect for a short course in the classroom or online. The text leads students to proficiency through proven word-building and competency-based techniques, while the online program, Medical Language Lab, tracks student progress until they've mastered the language of medicine. An access code inside new, printed texts unlocks the ebook and Medical Language Lab for students. Digital access can be purchased directly on FADavis.com. Instructors. Want to learn more? Request preview access to explore Medical Language Lab. See what students are saying online about the previous edition... Five Stars. "Just the book I needed for class with the Medical Language Lab online that I needed." - Josh, Online Reviewer Fantastic. " ...really easy to understand. I love the color coding, simple language, repetition, and regular practice questions. The online component of the book is also really helpful and well done, highly recommend using it." - Sam, Online Reviewer TextNow in its 3rd Edition, Medical Terminology Express adapts Barbara Gylys's proven word-building techniques for the short-course. Organized by body system, this text demonstrates the connection between anatomical structures and associated medial word roots. Medical Language Lab Online. Interactive. Progressive. Medical Language Lab guides students step by step from basic through advanced levels of proficiency to become confident medical language speakers. A wealth of audio case studies, progressive exercises, lecture videos, and a pronunciation guide and activities, plus an integrated e-book version of the text, offer multiple paths to learning success. This immersive, multimedia experience guides students and tracks their progress as they apply word-building concepts for practice and application.

Gait analysis is the study of the walking or running pattern of an individual. This can include spatial and temporal measurements such as step length, stride length and speed along with angular measurements of various joints and the interplay between various parts like the foot, hip, pelvis or spine when walking. Gait analysis can be used to assess clinical conditions and design effective rehabilitation; for example, following limb injury or amputation, or other disorders such as a stroke or Parkinson's diagnosis. It can be used to influence intervention decisions, such as whether a patient should undergo surgery, further physiotherapy, or begin a particular treatment regime. Gait analysis can also be used in sports science to monitor and review performance and technique. Gait can be recorded in a variety of ways, including pressure sensors, force plates, in-shoe pressure systems, through marker-based or marker-less systems using various cameras or sensors to calculate body positions in a set sequence of movements. This book focuses on both the hardware systems for collecting data as well as data visualisation and mathematical models for interpreting the data. It is written by a range of international researchers from academia, industry, and clinical settings, providing a complete overview of gait analysis technologies suitable for an audience of engineers in rehabilitation technologies or other biomedical engineering fields.

The game of American football may be the greatest team sport that exists. It epitomizes the need of a "team" first approach to achieve the desired success. Success is often measured as the hoisting of a championship trophy, which involved a journey that required discipline, perseverance, sacrifice, and hard work. These traits are the backbone of success in football, but more importantly they are the backbone or blueprint for success in life. The Science of American Football provides an in-depth discussion on the physiology of the game of American football, including the physiological strain associated with playing in various environmental extremes. Acclimatization, preparation, and medical issues associated with each of these environmental extremes are discussed as well as medical issues occurring during the athlete's playing career (common sites of injury) and potential risks arising post-career (e.g. neurological dysfunction, arthritic joints, obesity). The book goes on to consider aspects of player selection and preparation, including discussion of evidence-based physical conditioning programs, appropriate nutrition, and specific dietary supplementation for the American football player. The Science of American Football is the first book to focus on the physiology, science, and medical issues associated with the game of American football and will be key reading for students of coaching and exercise science as well as those with a keen interest in understanding the science of American football, such as coaches and players.