NMDA Receptor Protocols (Hardcover, 1999 ed.)

Min Li and a panel of hands-on experimentalists detail state-of-the-art molecular techniques for studying NMDA ligand-gated ion channels and developing assays for nontherapeutic lead selection. The topics range from cDNA cloning to in vitro and in vivo investigation of the channel complex in the mammalian brain. Additional topics include the biochemical analysis of the channel protein and the construction of various heterologous systems for both basic research and high throughput screens (HTS) for pharmaceutical chemicals. Although the focus is on NMDA receptors, the methods are applicable to other ligand-gated ion channels and with some modification may be extended to related membrane signaling receptors. NMDA Receptor Protocols offers today's scientists powerful methods for basic research on NMDA receptor structure and function, as well as enormous opportunities for clinical investigation toward the development of novel bioactive compounds.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 128
Release date:	April 1999
First published:	1999
Editors:	Min Li
Dimensions:	229 x 178 x 15mm (L x W x T)
Format:	Hardcover
Pages:	196
Edition:	1999 ed.
ISBN-13:	978-0-89603-713-7
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical laboratory testing & techniques Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Science & Mathematics > Biology, life sciences > Human biology & related topics > General
LSN:	0-89603-713-4
Barcode:	9780896037137

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