The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics.
Key Features
* Covers all aspects of the aging skeleton in one comprehensive volume
* Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass
* Provides a thorough discussion of fractures, one of the major consequences of the aging skeleton
* Reviews current therapeutic approaches and methods
* Written by internationally renowned authors and edited by leaders in the field
* Is the only book available on this subject

Platelets are fragments of blood cells that occur in the blood of vertebrates and are associated with blood clotting. Scientists have made great strides in recent years in understanding what stimulates platelets to form blood clots at the molecular level and in developing drugs to inhibit platelet action. Their work has a direct effect on millions of people who deal with cardiovascular disease, strokes, surgery, physical trauma, and other conditions. While references to platelet function have been included in some large texts, there has not been a basic reference manual that researchers and clinicians can use in their daily work until now.
Platelet Protocols fills the need for a straightforward and comprehensive laboratory manual on current procedures for evaluating and analyzing platelet function and abnormalities. It is an easy-to-read, understandable resource which can be kept at the bench and referred to frequently by scientists, clinicians, and laboratory staff involved in platelet related areas. Topics range from the basics of anticoagulants to the latest developments in platelet testing.
Key Features
Includes:
* A basic introduction to platelet anatomy and physiology
* Testing procedures for new anti-platelet therapies
* Descriptions of platelet function abnormalities
* Therapeutic approaches to inhibition of platelet function
* Step-by-step methodologies with clear explanations
* Helpful appendixes of recipes, instructions, sources of reagents, and more

Humans possess the most expressive faces in the animal kingdom. Adam Wilkins presents evidence ranging from the fossil record to recent findings of genetics, molecular biology, and developmental biology to reconstruct the fascinating story of how the human face evolved. Beginning with the first vertebrate faces half a billion years ago and continuing to dramatic changes among our recent human ancestors, Making Faces illuminates how the unusual characteristics of the human face came about-both the physical shape of facial features and the critical role facial expression plays in human society. Offering more than an account of morphological changes over time and space, which rely on findings from paleontology and anthropology, Wilkins also draws on comparative studies of living nonhuman species. He examines the genetic foundations of the remarkable diversity in human faces, and also shows how the evolution of the face was intimately connected to the evolution of the brain. Brain structures capable of recognizing different individuals as well as "reading" and reacting to their facial expressions led to complex social exchanges. Furthermore, the neural and muscular mechanisms that created facial expressions also allowed the development of speech, which is unique to humans. In demonstrating how the physical evolution of the human face has been inextricably intertwined with our species' growing social complexity, Wilkins argues that it was both the product and enabler of human sociality.

Measure joint range of motion with the manual that set the standard. Here is all of the guidance you need to identify impairments successfully and assess rehabilitation status effectively. Thoroughly updated and revised to reflect today's most current and complete research, the 5th Edition of this classic book retains the unique features that have set this manual apart as the reference of choice. For each measurable joint in the body, you'll find a consistent, easy-to-follow format and exceptional photographs that depict range of motion and alignment, making it easy for you to visualize the examination and technique for each joint motion and muscle length test. See what students are saying online about the previous edition... Great book "This book is a great guide to goniometry. I especially love the Appendix that has all the normal values. It's a must have for anyone starting out in physical therapy." Measurements made easy "This book is helpful because there are actual photographs that show you how to measure various ROM's. No confusing drawings. just pictures. So helpful. They also do a great job of summarizing the most important tips for each joint (i.e. normal ROM's, where to place the goni, etc.)

Volume 5 in the series "Advances in Structural Biology" is based upon a selection of articles presented at the Workshop on Molecular Bio-physics of the Cytoskeleton: Microtubule Formation, Structure, Function, and Interactions (August 18-22 1997 at the Banff Conference Centre in Banff, Alberta, Canada). Its main objective was to review the state-of-the-art of the field and stimulate a multidisciplinary investigation into the molecular biology of the cytoskeleton, which is amply manifested in the articles selected and published in this volume.

The Myocardium, Second Edition is a comprehensive presentation of cardiac function, including ultrastructure, cellular development and morphogenesis, ion channels, ion transporters, excitation-contraction coupling and calcium compartmentation, mechanics and force production, and energy metabolism. The Second Edition presents the new molecular, subcellular, and cellular developments which have occurred in this rapidly expanding field during the past 22 years.
Key Features
* Comprehensive overview of all aspects of heart function at the cellular, subcellular, and molecular level
* Integrates molecular events to give understanding of global cardiac function
* Includes basis of important pathological states

Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease.
Key Features
* Edited by "fathers of the field"
* An expanded version of a classic AP text
* Complete coverage of a fast-growing field

Sports vision is a relatively new but fast expanding area of multi-disciplinary eye care involving not only optometrists but also dispensing opticians, ophthalmologists, athletes, sports organisations and coaches. This book deals with optimising safe and efficient vision in sport. Sports vision will be essential reading for everyone involved in sport wishing to optimise vision particularly optometrists but also ophthalmologists, athletes and trainers. 'For practitioners wishing to develop an active interest in the subject this book acts as a valuable guide to how they need to develop both their optometric and dispensing skills.' - Journal of British Contact Lens Assoc., January 1996 '..excellent.' - The Optician, March 1996 * NEW IN PAPERBACK * * * Visual training, injuries and prevention, setting up a practice, legal considerations and many other aspects of sports vision are covered in detail.

Autophagy Processes and Mechanisms details the process of autophagy and its significance in diseases and aging. It provides insights into autophagy mechanisms and processes to broaden our understanding. By collecting recent progress on several aspects of the autophagy process, it provides a more integrative perspective and serves as a resource that can influence future research initiatives in the field. This new book is appropriate for basic and applied researchers in cell biology, biologists and those working in the pharmaceutical sciences.

This book discusses the importance of oxidative stress, related biomarkers, and its diagnostic methods including bio-analytical and advanced detection systems. Oxidative stress is associated with diminished capacity of a biological system to overcome the overproduction of reactive oxygen species. Since oxidative stress has been suggested as a causative factor in many diseases, its prevention is vital, and there is an urgent need for oxidative stress monitoring using in vitro and in vivo models. Interdisciplinary approaches have lead to the development of various oxidative stress monitoring models for real-world clinical and biomedical applications. The development of such methods requires a broad understanding of biology, chemistry, molecular biology, immunology and microbiology. As such, the book is a valuable resource for students, researchers and clinicians interested in the fundamental as well as applied aspects of oxidative stress associated diseases.

Learn the basics and more of gastrointestinal diseases. Gastrointestinal diseases have become a major medical, social and economic burden worldwide. The larger the number of patients suffering from gastric ulcer and colorectal cancer, the greater the need to properly diagnose and cure. This book is a comprehensive guide through GI diseases, which can be used by practitioners and patients. It will allow: - to explore the mechanisms underlying GI diseases - to accurately diagnose and find the best treatment - to learn how to alleviate GI disease symptoms by changing diet and lifestyle This guide has been written by experts in the field who understand the needs of doctors and their patients. With this book, you will make sure that the GI disease can be properly managed.

Vast numbers of different prokaryotic microorganisms shape the biosphere, with diverse metabolic capabilities. Determination of genome sequences for a wide range of bacteria and archaea now requires an in-depth knowledge of prokaryotic metabolic function to give biochemical, physiological and ecological meaning to the genomic information. This new edition describes up-to-date knowledge of the key metabolic processes that occur under different conditions, and the cellular processes that determine prokaryotic roles in the environment, biotechnology and human health. Essential for students of microbiology, applied microbiology, biotechnology, genomics and systems biology, this advanced textbook covers prokaryotic structure, composition, nutrient transport, biosynthesis and growth. Newly characterised metabolic pathways are included, as well as the latest understanding of metabolic regulation and stress responses. Additionally, the link between energetics, growth and survival is discussed as well as the maintenance of genetic integrity by the bacterial immune system.

First published in 1983 this book provides a review of the fundamentals of the biology and mechanics of human skin. The major theme is the interaction between and dependence of the integrity of skin on, cell turnover, nutrition, control mechanisms and disease. Mechanical, thermal and electrical properties are presented separately in a way that should allow the mathematically inexperienced reader to understand the principles but with sufficient detail to permit development of more advanced ideas. Discussion of environmental effects on skin includes cosmetics, solar radiation and clinical treatments. An account of methods of wound closure and of the recent attempts to find a substitute for skin completes an overview of this fascinating tissue.

Surface palpation is a valuable method for clinicians in detecting and treating a variety of injuries and medical conditions. A Clinical Guide to Surface Palpation, Second Edition With HKPropel Online Video, is a comprehensive guide that will help both students and health care professionals become proficient in these techniques so they can successfully assess and treat their patients. Using a simple step-by-step approach, A Clinical Guide to Surface Palpation, Second Edition, provides concise explanations of palpation techniques, organized by regions of the body. A brief overview of skeletal and muscle anatomy is offered for each region-including coverage of bony tissue, soft tissue, and neurovascular structures-to facilitate a better understanding of the relationship between structures and how they function together, leading to improved clinical examination skills. Tips for palpating bony landmarks are also discussed. Formerly titled A Clinical Guide to Musculoskeletal Palpation, this second edition has been expanded to include information on visceral palpation. One of very few textbooks that teaches readers how to examine the abdomen and pelvis, it recognizes the profound effect these structures can have on the function of the neuromuscular system. The visual aspect of the second edition has also been significantly upgraded. Anatomical overlays have been added to the numerous photos depicting proper technique to provide a clear view of the exact structures lying beneath the surface. More than 50 related online video clips, delivered through HKPropel, have also been added to showcase real demonstrations of common clinical palpation techniques. The skills are demonstrated in a step-by-step format to help readers understand the nuances of difficult techniques. This text also includes several learning aids to enhance anatomical knowledge and clinical skills. Clinical Pearls and notes throughout the text offer clinically relevant guidance alongside information on body structure identification and assessment. Each chapter concludes with a case study presenting a common clinical condition as well as review questions that prompt readers to apply their new understanding and proficiency. The most comprehensive resource of its kind, A Clinical Guide to Surface Palpation, Second Edition, fosters a strong foundation in anatomical knowledge to optimize the development and execution of palpation skills. It is a must-have for all practitioners, instructors, and students in the manual therapy professions. CE exam available! For certified professionals, a companion continuing education exam can be completed after reading this book. A Clinical Guide to Surface Palpation Online CE Exam, Second Edition, may be purchased separately or as part of the A Clinical Guide to Surface Palpation, Second Edition With CE Exam, package that includes both the book and the exam. Note: A code for accessing the online videos is included with all new print books.

This is the first book to explore the science underlying the concept of "koku", which is central to an understanding of the palatability of food within Japanese cuisine and is attracting increasing interest among food scientists and professionals worldwide. Koku may be defined as the sensation that results from the complexity of the food (i.e., its richness or body), its lingering aftertaste or persistence, and its heartiness in terms of taste, aroma, and texture. A variety of substances have been found to impact significantly on koku, including umami substances, phytosterols, certain aromatic compounds, and kokumi substances. In Koku - Food Science and Physiology, readers will find full explanation of the conceptual aspects and the latest research results on a wide range of topics, including the relevant flavor chemistry and sensory analysis. Written by leading scientists in the field, the book will be a valuable resource for students and researchers in the fields of food chemistry, nutritional science, taste physiology, and neuroscience, as well as for professionals in the food industry.

Challenging and provocative overviews are presented in Volume 40 of Current Topics in Membranes. Topics on cell lipids vary from basic themes such as biosynthesis and membrane distribution to the role of lipids in intracellular signaling and membrane flow. This single volume also highlights the roles of lipids in eukaryotic cells and discusses organization of lipids in microdomains.

What makes the heart beat faster or slower? How do tightrope walkers keep their balance? Why does spinning fast cause dizziness? Explore the mysteries and the workings of the human body through this fascinating collection of ideas, projects, and activities. Have fun while you learn about everything from the body’s basic building blocks to how the brain receives messages from other parts of the body. Make a model of a human cell that you can eat for dessert. Make a working model of a human lung from a soda bottle, a balloon, and a garbage bag. Through these and other activities, you’ll find out how your lungs supply air to your blood and your heart pumps blood throughout your body; how your body sees, hears, feels, smells, and tastes the world around it; how you lose and regain up to five pounds of skin every year; and much more. Most of the materials you need are already part of you; the rest you will easily find around the house or classroom. Every activity has been "child tested" and can be performed safely and cheaply in the classroom, at a science fair, or at home. Also available in the series from Janice VanCleave: Astronomy for Every Kid Biology for Every Kid Chemistry for Every Kid Dinosaurs for Every Kid Earth Science for Every Kid Geography for Every Kid Geometry for Every Kid Math for Every Kid Physics for Every Kid Kids, Join the Science for Every Kid Club …See inside for details.

Fully updated, revised and consolidated into one single volume, the fourth edition of Kinanthropometry and Exercise Physiology offers the best theoretically contextualised, practical resource for instructors and students available. Incorporating substantial sections on kinanthropometry, exercise physiology, energy systems and the application of science in health and high performance settings, the book covers the basics of measurement in exercise science through to advanced methods, and includes brand new chapters on: Pre-exercise screening and health risk stratification Functional movement assessment Point of care testing Anthropometry standards Anaerobic power and capacity History of exercise for health benefits Monitoring training loads in high-performance athletes Measuring game style in team sports Offering on-line access to newly developed exercise science measurement tools through the Exercise Science Toolkit - www.exercisesciencetoolkit.com - no other book offers such a complete resource, from the science of kinanthropometry and exercise physiology to their applications in health and performance, through practical, interactive learning. This book is an essential companion for students on any sport and exercise science-related degree programme and any instructor leading practical, laboratory-based classes.

Approx.572 pages

Dental Functional Morphology offers an alternative to the received wisdom that teeth merely crush, cut, shear or grind food and shows how teeth adapt to diet. Providing an analysis of tooth action based on an understanding of how food particles break, it shows how tooth form from the earliest mammals to modern-day humans can be understood using very basic considerations about fracture. It outlines the theoretical basis step by step, explaining the factors governing tooth shape and size and provides an allometric analysis that will revolutionize attitudes to the evolution of the human face and the impact of cooked foods on our dentition. In addition, the basis of the mechanics behind the fracture of different types of food, and methods of measurement are given in an easy-to-use appendix. It will be an important sourcebook for physical anthropologists, dental and food scientists, palaeontologists and those interested in feeding ecology.

The basic phenomena of intra- and intercellular communication and the transport signals within and between the cells controlling cardiac function are described and discussed in this volume. The amazing synchronization of millions of cells and billions of nanoscale molecular motors, ion gates, and ion pumps assure normal cardiac function; whereas disharmony and local transport and signal disruptions are the forecasters, and eventual causes, of pathologic conditions and heart failure.

Although this volume concentrates on basic phenomena, strong emphasis is given to the related clinical and pharmaceutical manifestations, and chapters have been contributed by molecular biologists, pharmaceutical experts, and cardiac scientists.

This volume will promote better understanding and, consequently, better clinical and pharmaceutical handling of the various aspects of cardiac pathophysiologies associated with electrical, mechanical, and metabolic and circulatory disorders in the cardiovascular system.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit" "www.blackwellpublishing.com/nyas"." ACADEMY MEMBERS Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member."

Laboratory Assessment and Exercise Prescription With HKPropel Online Video provides the practical knowledge and application skills for administering, interpreting, and applying data from health and fitness testing to create data-backed exercise prescription for clients. Focusing on the tests most widely used by professionals working in health, fitness, and allied health, the text covers both clinical and field tests so readers will be able to conduct assessments using a wide range of equipment and resources. Because the content is consistent with ACSM's Guidelines for Exercise Testing and Prescription, Eleventh Edition, both current and aspiring professionals can be assured they're using the most up-to-date methods and information available to best serve individual client needs and goals. Each lab demonstrates applications for the screenings and tests presented, with straightforward instructions for performing the assessment and collecting accurate data-both in the lab and when working with actual clients. Readers will learn about common errors made in assessments and will find out how to interpret results to assist clients in setting realistic health and fitness goals. Finally, readers will understand how the results of assessment will affect exercise program design and will learn how to combine data and client goals to design and prescribe an individualized exercise program. The book begins by taking the reader through the groundwork of working with clients and giving the reader experience with preparticipation screenings and basic fitness assessments. Next, assessment of body composition is addressed, along with assessment of resting metabolic rate, metabolic equations, and the application of those calculations within an exercise program. Aerobic and muscular fitness assessments are presented, followed by assessment of clinical variables, including pulmonary function testing, basic electrocardiography, and functional fitness testing. Two appendices cover common classes of medications (and how these medications may affect the exercise response) and basic emergency procedures for exercise physiology labs. Eleven case studies are also included, providing practical experience with interpreting data and designing an exercise program for a client. Related online video, delivered through HKPropel, demonstrates select assessments to improve comprehension of how to apply the content and develop skills for use with clients. Laboratory Assessment and Exercise Prescription is the essential guide for those studying for a fitness certification as well as for current health and fitness professionals who want a handy reference for testing. It offers the direction and understanding needed to accurately conduct exercise testing; analyze, interpret, and communicate data; and ultimately prescribe effective and safe exercise programs for clients. Note: A code for accessing online videos is included with all new print books.

The seven distinguished contributors to this volume illuminate not only the history of the biological and medical sciences but also the relationship between institutes and ideas which characterized the explosion of scientific investigation, especially in Germany. Besides William Coleman and Frederic L. Holmes, they include Robert G. Frank, Jr., Timothy Lenoir, John E. Lesch, Kathryn M. Olesko, and Arlene M. Tuchman. Scientific investigation was not new to the nineteenth century, but it was during that period that it began to be carried out on a scale large enough to become crucial to the welfare of nations. Much remains to be learned about how the forms of organization characteristic of the modern investigative enterprise originated. This book explores such questions in relation to one of the dominant experimental sciences of the century, physiology. Each author shows, through the examination of a specific institute or a specific subject, that the interplay between research, pedagogy, personal vision, and state or public interests can be studied to particular advantage in localized settings. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1988.