This book demonstrates the importance and potential role of Traditional Ecological Knowledge in foreseeing and curbing future global pandemics. The reduction of species diversity has increased the risk of global pandemics and it is therefore not only imperative to articulate and disseminate knowledge on the linkages between human activities and the transmission of viruses to humans, but also to create policy pathways for operationalizing that knowledge to help solve future problems. Although this book has been prompted by the COVID-19 pandemic, it lays a policy foundation for the effective management or possible prevention of similar pandemics in the future. One effective way of establishing this linkage with a view to promoting planet health is by understanding the traditional ecological knowledge of indigenous peoples with a view to demonstrating the significant impact it has on keeping nature intact. This book argues for the deployment of traditional ecological knowledge for land use management in the preservation of biodiversity as a means for effectively managing the transmission of viruses from animals to humans and ensuring planetary health. The book is not projecting traditional ecological knowledge as a panacea to pandemics but rather accentuating its critical role in the effective mitigation of future pandemics. This book will be of great interest to students and scholars of traditional ecological knowledge, indigenous studies, animal ecology, environmental ethics and environmental studies more broadly.

This book considers how largely accepted 'legal truths' about drugs and addiction are made and sustained through practices of lawyering. Lawyers play a vital and largely underappreciated role in constituting legal certainties about substances and 'addiction', including links between alcohol and other drugs, and phenomena such as family violence. Such practices exacerbate, sustain and stabilise 'addicted' realities, with a range of implications - many of them seemingly unjust - for people who use alcohol and other drugs. This book explores these issues, drawing upon data collected for a major international study on alcohol and other drugs in the law, including interviews with lawyers, magistrates and judges; analyses of case law; and legislation. Focussing on an array of legal practices, including processes of law-making, human rights deliberations, advocacy and negotiation strategies, and the sentencing of offenders, and buttressed by overarching analyses of the ethics and politics of such practices, the book looks at how alcohol and other drug 'addiction' emerges and is concretised through the everyday work lawyers and decision makers do. Foregrounding 'practices', the book also shows that law is more fragile than we might assume. It concludes by presenting a blueprint for how lawyers can rethink their advocacy practices in light of this fragility and the opportunities it presents for remaking law and the subjects and objects shaped by it. This ground-breaking book will be of interest not only to those studying and working within the field of alcohol and drug addiction but also to lawyers and judges practising in this area and to scholars in a range of disciplines, including law, science and technology studies, sociology, gender studies and cultural studies

This unique volume provides the latest information on secondary metabolites obtained from selected organisms (plants or microorganisms) that have beneficial effects in the treatment of cardiovascular diseases and an ability to offer protection against their progress. A detailed description of their source, chemistry and mechanism of action is provided, together with results of clinical studies. Here, a clear connection is made between chemical structures, in vitro studies and their clinical significance.The topic is extensive and the audience gains an understanding of the medicinal applications of these groups of secondary metabolites that have the potential to improve cardiovascular health. Features: The latest information on secondary metabolites with beneficial effects in the treatment of cardiovascular diseases. Written by an outstanding team of authors, their work provides new insights into the beneficial effects of different components present in well known plant products, evidencing their impressive cardiovascular effects. This volume discusses novel targets to screen for new drugs and the need for data obtained from clinical studies using natural products in order to better analyze the significance of in vitro experimental data. Here the reader will find a unique and timely volume with an international flavor. This book describes the source, chemistry and mechanism of action of natural products with the potential to improve cardiovascular health.

This book explores the normalization of HIV and AIDS, reflecting upon the intended and unintended consequences of the multifarious "AIDS industry." The Normalization of the HIV and AIDS Epidemic in South Africa deals with the manner in which the HIV and AIDS epidemic has become such a well-known disease with such wide-ranging ramifications. With its focus on the "AIDS industry," this book examines issues such as the framing of the HIV and AIDS epidemic in a manner that greatly fostered notions of stigmatization and moralization. This book looks at the complexities of dealing with the epidemic in contemporary South Africa, examining the difficulties of addressing the social aspects of a disease in the context of increased focus on technological quick-fix solutions. De Wet explores these issues thoroughly, looking at the social determinants of the spread of the disease as well as the configuration and the nature of the responses to it, and their increasing marginalization as factors to address in an era of increased biomedicalization and concomitant normalization. This book will intrigue scholars and students of public health, global health care, medical sociology, and African Studies.

Recalibrating Juvenile Detention chronicles the lessons learned from the 2007 to 2015 landmark US District Court-ordered reform of the Cook County Juvenile Temporary Detention Center (JTDC) in Illinois, following years of litigation by the ACLU about egregious and unconstitutional conditions of confinement. In addition to explaining the implications of the Court's actions, the book includes an analysis of a major evaluation research report by the University of Chicago Crime Lab and explains for scholars, practitioners, administrators, policymakers, and advocates how and why this particular reform of conditions achieved successful outcomes when others failed. Maintaining that the Chicago Crime Lab findings are the "gold standard" evidence-based research (EBR) in pretrial detention, Roush holds that the observed "firsts" for juvenile detention may perhaps have the power to transform all custody practices. He shows that the findings validate a new model of institutional reform based on cognitive-behavioral programming (CBT), reveal statistically significant reductions in in-custody violence and recidivism, and demonstrate that at least one variation of short-term secure custody can influence positively certain life outcomes for Chicago's highest-risk and most disadvantaged youth. With the Quarterly Journal of Economics imprimatur and endorsement by the President's Council of Economic Advisors, the book is a reverse engineering of these once-in-a-lifetime events (recidivism reduction and EBR in pretrial detention) that explains the important and transformative implications for the future of juvenile justice practice. The book is essential reading for graduate students in juvenile justice, criminology, and corrections, as well as practitioners, judges, and policymakers.

Master GIS Applications on Modelling and Mapping the Risks of Diseases Infections transmitted by mosquitoes, ticks, triatomine bugs, sandflies, and black flies cause significant rates of death and disease, especially in developing countries. Why are certain places more susceptible to vector-borne diseases? Modelling Interactions Between Vector-Borne Diseases and Environment Using GIS reveals how using geographic information systems (GISs) can provide a greater understanding of how vector-borne diseases are spread and explores the use of geographical techniques in vector-borne disease monitoring, management, and control. This text provides readers with a better understanding of the vector-borne disease problem and its impact on public health. Introduces New Spatial Approaches Based on Location and Environment The book exposes readers to information on how to identify vector hotspots, determine when and where they can occur, and eliminate vector breeding sites. Utilizing simple illustrations based on real data, as well as the authors' more than 20 years of experience in the field, this text combines key spatial analysis techniques available in modern GIS with real-world applications. It offers step-by-step instruction on developing vector-borne disease risk models at different spatial and temporal scales and helps practitioners formulate disease causation hypotheses and identify areas at risk. In addition, it addresses medical geography, GIS, spatial analysis, and modelling, and covers other factors related to the spread of vector-borne diseases. This book: Gives an overview of common vector-borne diseases, GIS-based mapping and modelling, impacts of climate change on vector distributions, and availability and importance of accurate epidemiologically relevant spatial data Describes modelling and simulating the prevalence of vector-borne diseases around the world Summarizes some key spatial techniques and how they can be used to aid in the analysis of geographical and attributed data Defines the concept of establishing and characterizing spatial data systems, including their quality, errors, references, and issues of scale, and building such a system from often quite separate, disparate sources Shows how to develop weather-based predictive modelling, which can be used to predict the weekly trend of vector abundance Provides a GIS case study for modelling the future potential distribution of vector-borne disease based on different climatic change scenarios Modelling Interactions Between Vector-Borne Diseases and Environment Using GIS combines spatial analysis techniques available in modern GIS, together with real-world applications to provide you with a better understanding of ways to map, model, prevent, and control vector-borne diseases.

This book builds on the person-centred medicine movement to promote a shift in the philosophy of care of distress. It discusses the vital importance of whole person health, healing and growth. Developing a new transdisciplinary concept of sense of safety, this book argues that the whole person needs to be understood within their context and relationships and explores the appraisal and coping systems that are part of health. Using clinical vignettes to illustrate her argument, Lynch draws on an understanding of attachment, and trauma-informed approaches to life story and counsels against an over-reliance on symptom-based fragmentation of body and mind. Integrating literature from social determinants of health, psychology, psychotherapy, education and the social sciences with new research from the fields of immunology, endocrinology and neurology, this broad-ranging book is relevant to all those with an interest in person-centred healthcare, including academics and practitioners from medicine, nursing, mental health and public health.

Medical Risk Prediction Models: With Ties to Machine Learning is a hands-on book for clinicians, epidemiologists, and professional statisticians who need to make or evaluate a statistical prediction model based on data. The subject of the book is the patient's individualized probability of a medical event within a given time horizon. Gerds and Kattan describe the mathematical details of making and evaluating a statistical prediction model in a highly pedagogical manner while avoiding mathematical notation. Read this book when you are in doubt about whether a Cox regression model predicts better than a random survival forest. Features: All you need to know to correctly make an online risk calculator from scratch Discrimination, calibration, and predictive performance with censored data and competing risks R-code and illustrative examples Interpretation of prediction performance via benchmarks Comparison and combination of rival modeling strategies via cross-validation Thomas A. Gerds is a professor at the Biostatistics Unit at the University of Copenhagen and is affiliated with the Danish Heart Foundation. He is the author of several R-packages on CRAN and has taught statistics courses to non-statisticians for many years. Michael W. Kattan is a highly cited author and Chair of the Department of Quantitative Health Sciences at Cleveland Clinic. He is a Fellow of the American Statistical Association and has received two awards from the Society for Medical Decision Making: the Eugene L. Saenger Award for Distinguished Service, and the John M. Eisenberg Award for Practical Application of Medical Decision-Making Research.

The Organic Food Handbook examines an important trend and provides a concise, easy-to-follow guide to eating and buying organic food. It clearly explains what organic food is and how it is produced, and where to buy it at the most economical prices. The book, also, covers: how conventional food poses threats to our health and environment; why organic is a healthier, safer choice for us all; how organic certification ensure that organic food is produced to the highest standards; and, how the high costs of conventional foods are hidden in the subsidies we support. As this book shows, organic food clearly benefits our personal health as well as the environment. Eating organic contributes to a more sustainable world and a healthier future.

Feeding your baby is a big part of the first year. It can be an exciting and enjoyable time but also one that can raise many questions and concerns. What to give them? How much? And when? It can feel like everyone has an opinion on what you should do and what worked for them, with a confusing array of information online to wade through. Let's talk about feeding your baby helps support you through this. Covering breast and formula feeding, mixed feeding, starting solids and more, this supportive and non-judgemental guide brings you the evidence, top tips and lots of support to answer all your feeding questions. Focusing on both the practicalities and emotions attached to feeding decisions, it will answer your questions big and small, supporting you to confidently feed your baby as they grow, in whatever way works for your family. With expert contributors and quotes from parents, Professor Amy Brown's authoritative but easy-to-read style ensures that this book will inform and reassure anyone wanting to know more about how to support their baby to be a healthy and happy eater however they decide to feed them.

This practical guide will assist healthcare practitioners to manage and meet the physical and psycho-social needs of people with complex chronic diseases/long-term conditions. Systematic and evidence-based care which takes account of the expert patient and reduces unnecessary hospital admissions is vital to support those with long-term conditions/chronic diseases and those who care for them. Effective management of long-term conditions is an essential part of contemporary nursing and healthcare policy and practice globally. Reflecting recent changes in the curriculum, this fully updated multidisciplinary edition highlights the key issues in managing long-term conditions. It provides a practical and accessible guide for nurses and allied health professionals in the primary care environment including: case studies on HIV and dementia and content on mental health the physical and psychosocial impact of living with long-term conditions effective case management self-management and the expert patient behavioural change strategies and motivational counselling Packed with helpful, clearly written information, Managing Long-term Conditions and Chronic Illness in Primary Care includes case studies, fact boxes and pointers for practice. It is ideal reading for pre- and post-registration nursing students taking modules on long-term conditions and will be a valuable companion for pre-registration students on community placements.

The Green Lunch Box is packed with delicious, healthy, plant-based lunches to help you save the planet in your lunch break. Making your own lunch just a few times a week saves money, packaging and precious time. Discover simple, short recipes for hot boxes, soups, salads, wraps and snacks that make the most of your everyday fresh and store cupboard ingredients. Learn to love your leftovers, master the art of batch cooking and discover ingenious sustainable ways to pack (and eat) your lunch. Features sixty beautifully illustrated recipes, including: Smashed beets and rainbow salad with hazelnut dukkha, Burrito box with charred sweetcorn, avocado, habanero peppers and lime salsa, Black lentil, almond and coconut dahl with crispy cumin cauliflower, Courgette, carrot, apple and lime slaw with toasted pumpkin seeds, Spicy parsnip soup with crispy harissa chickpeas, Peanut butter, lime, chilli and rocket bagel, Mushroom, white bean, miso and leek parcels

Provides a concise and intuitive overview of the role of statistics in surgical practice. Uses no mathematics but includes narrative descriptions of statistical concepts. Includes topics of specific interest to surgeons. Provides real surgical examples to illustrate applications.

Originally published in 1945, this is a concise account of the remarkable experiment with boys carried out by the author of The Hawkspur Experiment. The war put this latter experiment into abeyance, but gave its author an opportunity to practice his principles on a group of younger difficult boys. Aged from eight to fourteen, these boys were the "throw-outs" of the Evacuation Scheme, but before the Barns experiment had been long in operation troublesome boys were being evacuated not primarily to escape bombs, but in order that they might have the treatment that Barns provided. Barns was a Hostel-school initiated by the Society of Friends, where lawless boys made their own laws, and where the principle instrument in their reformation was not punishment but affection. So successful were the unconventional methods here described that sceptics were convinced, and Barns has now achieved a permanent place in the field of "the therapy of the dis-social." Today it would be described as a therapeutic community and is one of the earliest experiments of its kind that raised awareness and paved the way for further research in this area.

Originally published in 1987, Malcolm Hill examines the different ways in which parents share responsibility for looking after their pre-school children with other people, whether members of their social networks, formal groups or paid carers. He also looks at the reasons parents give for choosing and changing their particular arrangements. In this way he provides insights into a range of ideas which ordinary members of the public have about children's needs; the rights and responsibilities of mothers and fathers; and how children think and feel. Marked differences are described in the social relationships of families and in notions about who is acceptable as a substitute carer for children, in what circumstances and for what purpose. Several of these contrasts are linked to attitudes and life-conditions which are affected by social class. The book identifies possible consequences for individual children's social adaptability resulting from these patterns of care. It suggests that people working with the under-fives could profit from adapting their activities and services to children's previous experiences of shared care and families' differing expectations about groups for children.

Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects ModelsMixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whole population of individuals at the same time. Easy-to-Use Techniques and Tools for Real-World Data ModelingThe book first shows how the framework allows model representation for different data types, including continuous, categorical, count, and time-to-event data. This leads to the use of generic methods, such as the stochastic approximation of the EM algorithm (SAEM), for modeling these diverse data types. The book also covers other essential methods, including Markov chain Monte Carlo (MCMC) and importance sampling techniques. The author uses publicly available software tools to illustrate modeling tasks. Methods are implemented in Monolix, and models are visually explored using Mlxplore and simulated using Simulx. Careful Balance of Mathematical Representation and Practical ImplementationThis book takes readers through the whole modeling process, from defining/creating a parametric model to performing tasks on the model using various mathematical methods. Statisticians and mathematicians will appreciate the rigorous representation of the models and theoretical properties of the methods while modelers will welcome the practical capabilities of the tools. The book is also useful for training and teaching in any field where population modeling occurs.

The get-it-over-with-quickly approach to statistics has been encouraged - and often necessitated - by the short time allotted to it in most curriculums. If included at all, statistics is presented briefly, as a task to be endured mainly because pertinent questions may appear in subsequent examinations for licensure or other certifications. However, in later professional activities, clinicians and biomedical researchers will constantly be confronted with reports containing statistical expressions and analyses. Not just a set of cookbook recipes, Principles of Medical Statistics is designed to get you thinking about data and statistical procedures. It covers many new statistical methods and approaches like box plots, stem and leaf plots, concepts of stability, the bootstrap, and the jackknife methods of resampling. The book is arranged in a logical sequence that advances from simple to more elaborate results. The text describes all the conventional statistical procedures, and offers reasonably rigorous accounts of many of their mathematical justifications. Although the conventional mathematical principles are given a respectful account, the book provides a distinctly clinical orientation with examples and teaching exercises drawn from real world medical phenomena. Statistical procedures are an integral part of the basic background needed by biomedical researchers, students, and clinicians. Containing much more than most elementary texts, Principles of Medical Statistics fills the gap often found in the current curriculum. It repairs the imbalance that gives so little attention to the role of statistics as a prime component of basic biomedical education.

When Peter Piot was in medical school, a professor warned, "There's no future in infectious diseases. They've all been solved." Fortunately, Piot ignored him, and the result has been an exceptional, adventure-filled career. In the 1970s, as a young man, Piot was sent to Central Africa as part of a team tasked with identifying a grisly new virus. Crossing into the quarantine zone on the most dangerous missions, he studied local customs to determine how this disease-the Ebola virus-was spreading. Later, Piot found himself in the field again when another mysterious epidemic broke out: AIDS. He traveled throughout Africa, leading the first international AIDS initiatives there. Then, as founder and director of UNAIDS, he negotiated policies with leaders from Fidel Castro to Thabo Mbeki and helped turn the tide of the epidemic. Candid and engrossing, No Time to Lose captures the urgency and excitement of being on the front lines in the fight against today's deadliest diseases.

This book provides a theoretical framework and related technical skills for investigating climate change and its public health consequences and responses with a focus on urban settings, and in particular Hong Kong, a subtropical metropolis in Asia. Specifically, the book examines the impact of climate change on health in terms of mortality, hospital admissions and help-seeking, as well as key response strategies of adaptation and mitigation. Many existing books tend to consider the relationship of climate change and public health as two connected issues divided into various discrete topics. Conversely, this book explicitly applies public health concepts to study the human impact of climate change, for example, by conceptualising climate change impact and its alleviation, mitigation and adaptation in a public health framework. Overall, this volume summarises what is known about climate change and health and ignites further debates in the area, especially for urban subtropical communities from within a wider global perspective. This book will be of great interest to students and scholars of environmental health, public health, climate change, urban studies and Asian studies.

This book presents a novel and accessible way to learn about designing and conducting social research. Unlike traditional social research methods books, it provides a 'real world' account of social researchers' experiences and learning achieved through conducting research in a variety of fields. It contains an eclectic collection of research and advice for conducting research from social researchers with varying backgrounds. Suggestions are made in relation to gaining access to research sites, conducting research on sensitive topics such as suicide, child sexual abuse and homelessness, ensuring the inclusive participation of participants with intellectual disabilities and children. Also included are discussions of conducting practitioner research, conducting research on individual change, psychoanalytically informed research, documentary research and post qualitative research. Other chapters focus on criticality in research on topics that have become politicised and moralised, ensuring that research conducted is credible and how knowledge in research is constructed through both the theoretical framework used and how it is conducted. Bringing together a diverse collection of social research projects, Designing and Conducting Research in Social Science, Health and Social Care will be of interest to students, educators and researchers in the social sciences and professionals in related areas.

Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means using dedicated statistical software. There are several software packages, all with their specific objective. Finally, all packages are free to use, are versatile with problem-solving, and are interactive with R and OpenBUGS. This book continues to cover a range of techniques related to oncology that grow in statistical analysis. It intended to make a single source of information on Bayesian statistical methodology for oncology research to cover several dimensions of statistical analysis. The book explains data analysis using real examples and includes all the R and OpenBUGS codes necessary to reproduce the analyses. The idea is to overall extending the Bayesian approach in oncology practice. It presents four sections to the statistical application framework: Bayesian in Clinical Research and Sample Size Calcuation Bayesian in Time-to-Event Data Analysis Bayesian in Longitudinal Data Analysis Bayesian in Diagnostics Test Statistics This book is intended as a first course in bayesian biostatistics for oncology students. An oncologist can find useful guidance for implementing bayesian in research work. It serves as a practical guide and an excellent resource for learning the theory and practice of bayesian methods for the applied statistician, biostatistician, and data scientist.

The SARS-CoV-2 virus, and the associated COVID-19 pandemic, is perhaps the greatest threat to life, and lifestyles, the world has known in more than a century. The scholarship included here provides critical insights into the ethics and ideologies, inequalities, and changed social understandings that lie at the heart of this pandemic. This volume maps out the ways in which the pandemic has impacted (most often disproportionately) societies, the successes and failures of means used to combat the virus, and the considerations and future possibilities - both positive and negative - that lie ahead. While the pandemic has brought humanity together in some noteworthy ways, it has also laid bare many of the systemic inequalities that lie at the foundation of our global society. This volume is a significant step toward better understanding these impacts. The work presented here represents a remarkable diversity and quality of impassioned scholarship and is a timely and critical advance in knowledge related to the pandemic. This volume and its companion, COVID-19: Volume II: Social Consequences and Cultural Adaptations, are the result of the collaboration of more than 50 of the leading social scientists from across five continents. The breadth and depth of the scholarship is matched only by the intellectual and global scope of the contributors themselves. The insights presented here have much to offer not just to an understanding of the ongoing world of COVID-19, but also to helping us (re-) build, and better shape, the world beyond.

This book delves into this almost unchartered territory, documenting the lived experiences of sex workers in Bangladesh, considering the complex realities of their day-to-day lives and the ways they negotiate their working conditions and relationships. Despite being the most common form of female deviance and criminality globally, we know very little about sex work in Asia and the global south. Drawing on feminist frameworks, it shows that the experiences of sex workers vary widely depending on the ways they enter the sex trade, their modes of operation, and relationships with significant others. Towards a Southern Approach to Sex Work contributes to feminist scholarship on sex work, by offering a much needed southern perspective, drawing on culturally specific data. It argues that the lived experience of sex workers comprises both victimhood and agency, deception and resilience, and that it is the management of these relationships that enable sex works to avoid social marginalization and alienation. An accessible and compelling read, this will appeal to students and scholars of criminology, sociology, gender studies, south Asian studies, cultural studies, social theory and policy makers. In addition, it will engage all those interested in learning more about how the sex trade operates in Bangladesh.

1. Cutting-edge synthesis of key areas in substance use and misuse, which sets it apart from competing biopsychology textbooks 2. Each chapter is written by leading experts on the topic in question, recruited from research teams around the world (including UK, US, Europe, New Zealand, Canada, Asia), who have a detailed knowledge of the relevant literature. 3. Important methodological and ethical issues are explored, with reference to various cultural contexts.