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Inflammation (Paperback, Softcover reprint of the original 1st ed. 1978)
Loot Price: R3,115
Discovery Miles 31 150
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Inflammation (Paperback, Softcover reprint of the original 1st ed. 1978)
Series: Handbook of Experimental Pharmacology, 50 / 1
Expected to ship within 10 - 15 working days
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Throughout the centuries, inflammation has been considered as a
disease in itself. This misconception arose from the inability to
distinguish between inflammatory changes and the insults which
induce them. The understanding of the distinction between the
genesis of inflammation and the tissue reactions that follow is
attributed to JOHN HUNTER, who, at the end of the 18th century,
substantially contributed to the analysis of inflammation in
objective terms. Today, however, we are still trying to find
explanations for Celsus' Signs in terms of structural and
functional changes occurring in the inflamed tissue. There are
drugs which modulate these signs but, without a detailed knowledge
of the basic physiopathological events, it is impossible to
understand their mechanism of action. Notwithstanding, the effects
of anti inflammatory drugs provided new knowledge of the relevance
of the signs and symptoms to the sequence of biochemical and
morphological changes occurring in inflammation. When we accepted
the invitation to edit a Handbook on Inflammation and Anti
Inflammatory Drugs, we were aware of the magnitude of the task. We
knew the impossibility of covering the whole field in detail,
especially taking into account the rapid accumulation of
experimental knowledge which would, in all likelihood, overtake the
process of publication."
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