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The Respiratory Burst and Its Physiological Significance (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R2,843
Discovery Miles 28 430
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The Respiratory Burst and Its Physiological Significance (Paperback, Softcover reprint of the original 1st ed. 1988)
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When phagocytes are exposed to a number of different stimuli, they
undergo dra matic changes in the way they process oxygen. Oxygen
uptake increases markedly, frequently more than 50-fold; the
phagocytes begin to produce large quantities of superoxide and
hydrogen peroxide; and they immediately begin to metabolize large
amounts of glucose by way of the hexose monophosphate shunt. This
series of changes has become known as the respiratory burst. It was
first believed that the major function of this respiratory burst
was to generate powerful antibacterial agents by the partial
reduction of oxygen. It is becoming apparent that the respiratory
burst has much wider application, and its physiological function in
many different biolog ical areas is clear. In this volume, we have
attempted to bring together the work of experts who have published
extensively on the involvement of the respiratory burst in
different physiological functions. In the first three chapters, Dr.
Borregaard and Dr. Berton and co-workers and Dr. Roos and
co-workers bring together what is known about the respiratory
burst. They present up-to-date versions of the biochemical and
metabolic activities associ ated with the burst. In Chapter 4, Dr.
Styrt and Dr. Klempner discuss the respiratory burst as it affects
cellular ion homeostasis. Dr. Cohen and Dr. Britigan (Chapter 5)
present some interesting data on the competition between the
respiratory burst and bacteria for oxygen. Dr. Dobrina and Dr."
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