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Liver Growth and Repair (Hardcover, 1998)
Loot Price: R5,942
Discovery Miles 59 420
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Liver Growth and Repair (Hardcover, 1998)
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Nelson Fausto The Greek myth of Prometheus with its picture of a
vulture feasting on its chained victimhas traditionallyprovided a
visualimageofliverregeneration. Itis apowerful and frightening
representationbut ifone were to substitute the vulture by a surgeon
and Prometheus by a patient laying on a properly prepared operating
table, the outcomeoftheprocedurewould not differ significantlyfrom
that describedbyGreek poets. Yet few of us who work in the field
have stopped long enough to ask where this myth originated. Did the
poet observe a case of liver regeneration in a human being? Was it
brilliant intuition or perhaps, literally, just a 'gut feeling' of
a poet looking for good rhymes that led to the prediction that
livers grow when part of the tissueisremoved?
Thisbookdoesnotattemptto solve these historical issues. Itdoes,
instead, cover in detail some of the major modem themes of research
on liver regen eration, injury and repair. As indicated in Dr. N.
Bucher's chapter, the modem phase ofexperimental studies on liver
regeneration started in 1931 with the publication by Higgins and
Anderson of a method to perform a two-thirds resection of the liver
of a rat. The technique described has 3 remarkable features: 1) it
is highly reproducible, resulting in the removal of 68% of the
liver, 2) it has minimal if any mortality, and 3) it consists only
of blood vessel ligation and does not involve cutting through or
wounding hepatic tissue.
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