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Taurine 8 - Volume 1: The Nervous System, Immune System, Diabetes and the Cardiovascular System (Paperback, 2013 ed.)
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Taurine 8 - Volume 1: The Nervous System, Immune System, Diabetes and the Cardiovascular System (Paperback, 2013 ed.)
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Taurine 8 represents the combined efforts of investigators on the
roles of the amino acid taurine on human health and disease. The
chapters covered in this book are directly derived from
presentations of the contributors at the 18th International Taurine
Meeting held in Marrakech, Morocco in April 2012. The purpose of
this book is to disseminate current findings on taurine's
contribution in several organ systems. This book covers the
following topics: Taurine in the Nervous System, Taurine in the
Immune System, Taurine and Diabetes, and Taurine and the
Cardiovascular System. Dr. Abdeslem El Idrissi, College of Staten
Island and Dr. William L'Amoreaux, College of Staten Island, were
co-chairs of the Organizing Committee for the meeting. Data
presented at this meeting provided compelling evidence that taurine
is not only cytoprotective in cardiomyocytes, but also is a potent
GABA agonist, whereby it can facilitate vasodilation of conducting
arteries. Taurine conjugates, such as taurine chloramine, may
protect cells from oxidative stress via increased HO-1 expression.
In adult rodents, taurine has a potent effect on plasma glucose
levels, likely through the release of insulin in pancreatic beta
cells. As a potential neurotransmitter, taurine is known to work
via the GABAergic system, but current research presented at this
meeting suggest that taurine may interact with glutamate and
serotonin receptors as well. Data are also presented to demonstrate
the protective roles of taurine on neurons in neuroblastoma.
Perhaps the most important and exciting presentation is the role of
taurine and alcohol: the combination may be lethal. Data are also
presented at this meeting of the potential role taurine may have as
an adjuvant treatment with cisplatin in chemotherapy.
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