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Taurine 8 - Volume 2: Nutrition and Metabolism, Protective Role, and Role in Reproduction, Development, and Differentiation (Paperback, 2013 ed.)
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Taurine 8 - Volume 2: Nutrition and Metabolism, Protective Role, and Role in Reproduction, Development, and Differentiation (Paperback, 2013 ed.)
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Taurine 8 represents the combined efforts of investigators on the
roles of the amino acid taurine on human health and disease. The
chapters covered in this book are directly derived from
presentations of the contributors at the 18th International Taurine
Meeting held in Marrakech, Morocco in April 2012. The purpose of
this book is to disseminate current findings on taurine's
contribution in several organ systems. This book covers the
following topics: Taurine in Nutrition and Metabolism, the
Protective Role of Taurine, and the Role of Taurine in
Reproduction, Development, and Differentiation. Dr. Abdeslem El
Idrissi, College of Staten Island and Dr. William L'Amoreaux,
College of Staten Island, were co-chairs of the Organizing
Committee for the meeting. Data presented at this meeting provided
compelling evidence that taurine is not only cytoprotective in
cardiomyocytes, but also is a potent GABA agonist, whereby it can
facilitate vasodilation of conducting arteries. Taurine conjugates,
such as taurine chloramine, may protect cells from oxidative stress
via increased HO-1 expression. In adult rodents, taurine has a
potent effect on plasma glucose levels, likely through the release
of insulin in pancreatic beta cells. As a potential
neurotransmitter, taurine is known to work via the GABAergic
system, but current research presented at this meeting suggest that
taurine may interact with glutamate and serotonin receptors as
well. Data are also presented to demonstrate the protective roles
of taurine on neurons in neuroblastoma. Perhaps the most important
and exciting presentation is the role of taurine and alcohol: the
combination may be lethal. Data are also presented at this meeting
of the potential role taurine may have as an adjuvant treatment
with cisplatin in chemotherapy.
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