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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases
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Heat Shock Proteins of Malaria (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R4,350
Discovery Miles 43 500
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Heat Shock Proteins of Malaria (Paperback, Softcover reprint of the original 1st ed. 2014)
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This book describes the role of heat shock proteins in the life
cycle of malaria parasites. The work includes a general
introduction on the structural and functional features of heat
shock proteins. The main focus is on the role of heat shock protein
families from Plasmodium falciparum, their role in protein folding
and in the development of malaria pathology. The functions of
individual families of heat shock proteins from plasmodium species
and their cooperation in functional networks is described.
Subcellular and extracellular organelles such as the apicoplast and
the Maurer's Clefts which are associated with plasmodium species,
are discussed in detail. The role of heat shock proteins in the
development and function of these organelles structures are
highlighted. Although conceding that heat shock proteins may not be
ideal antimalarial drug targets, prospects of targeting heat shock
proteins in antimalarial drug discovery either directly and/or in
combination therapies are explored.
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