0
Your cart

Your cart is empty

Books > Science & Mathematics > Biology, life sciences > Biochemistry

Buy Now

Neurochemical Aspects of Excitotoxicity (Paperback, Softcover reprint of hardcover 1st ed. 2008) Loot Price: R5,431
Discovery Miles 54 310
Neurochemical Aspects of Excitotoxicity (Paperback, Softcover reprint of hardcover 1st ed. 2008): Akhlaq A. Farooqui, Wei-Yi...

Neurochemical Aspects of Excitotoxicity (Paperback, Softcover reprint of hardcover 1st ed. 2008)

Akhlaq A. Farooqui, Wei-Yi Ong, Lloyd A Horrocks

 (sign in to rate)
Loot Price R5,431 Discovery Miles 54 310 | Repayment Terms: R509 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

About 40% of central nervous system synapses use glutamate as the neurotransmitter. Over-stimulation of glutamate receptors produces neuronal injury or death by excitotoxicity, which is closely associated with neurochemical and neuropathological changes involved in acute neural trauma (stroke, spinal cord trauma, and head injury) and neurodegenerative diseases such as Alzheimer disease, Parkinson disease, Huntington disease, amyotrophic lateral sclerosis (ALS), Creutzfeldt-Jakob disease, Guam-type amyotrophic lateral sclerosis/Parkinson dementia (ALS/PDC), and multiple sclerosis.

In the past decade, our understanding of the biochemistry, molecular biology, and neuropathology of the glutamate transporters and receptors has exploded. It is becoming increasingly evident that molecular mechanisms, which govern the transfer of the death signal from the neural cell surface to the nucleus, depend on lipid mediators and on cross talk among excitotoxicity, oxidative stress, and neuroinflammation, and that interactions among these three processes play a major role in neuronal cell death during acute neural trauma and neurodegenerative disease. These processes may be primary initiating points in neurodegeneration or they may be the end result of the neurodegenerative process itself.

Neurochemical Aspects of Excitotoxicity provides extensive insight into glutamate transporters and receptors, including their role in the brain with other neurochemical parameters in excitotoxicity, and possible treatments. This book will be of interest scientists already working in the field of excitotoxicity who are interested in gaining a broader understanding of this complicated subject area, as well as graduate students and neurologists who are curious about a common cause of neuronal injury and neurological disorders.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Release date: October 2010
First published: 2008
Authors: Akhlaq A. Farooqui • Wei-Yi Ong • Lloyd A Horrocks
Dimensions: 235 x 155 x 16mm (L x W x T)
Format: Paperback
Pages: 290
Edition: Softcover reprint of hardcover 1st ed. 2008
ISBN-13: 978-1-4419-2504-6
Categories: Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN: 1-4419-2504-X
Barcode: 9781441925046

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Fast This Way - Burn Fat, Heal…
Dave Asprey Paperback R336 Discovery Miles 3 360
Biochemistry
Owen McDougal, Mary Campbell, … Hardcover R1,389 R1,251 Discovery Miles 12 510
The Poisoners - On South Africa's Toxic…
Imraan Coovadia Paperback R320 R250 Discovery Miles 2 500
bundle available
Assessing Transformation Products of…
Joerg E. Drewes, Thomas Letzel Hardcover R4,902 Discovery Miles 49 020
NMR Spectroscopy in the Undergraduate…
David Soulsby, Laura J. Anna, … Hardcover R5,562 Discovery Miles 55 620
Mycotoxin Prevention and Control in…
Michael Appell, David Kendra, … Hardcover R3,427 R2,766 Discovery Miles 27 660
Chiral Pesticides - Stereoselectivity…
A. Wayne Garrison, Jay Gan, … Hardcover R2,759 Discovery Miles 27 590
Advances in Human Vector Control
J. Marshall Clark, Jeffrey Bloomquist, … Hardcover R2,646 Discovery Miles 26 460
Biobased Monomers, Polymers, and…
Patrick B. Smith, Richard B. Gross Hardcover R5,556 Discovery Miles 55 560
Flavor of Dairy Products
Keith R. Cadwallader, Mary Anne Drake, … Hardcover R2,280 Discovery Miles 22 800
Authentication of Food and Wine
Susan E. Ebeler, Gary R. Takeoka, … Hardcover R3,173 Discovery Miles 31 730
Measuring Metabolic Rates - A Manual for…
John R.B. Lighton Hardcover R1,977 Discovery Miles 19 770

See more

Partners