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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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Trace Amines - Comparative and Clinical Neurobiology (Hardcover, 1988 ed.)
Loot Price: R2,920
Discovery Miles 29 200
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Trace Amines - Comparative and Clinical Neurobiology (Hardcover, 1988 ed.)
Series: Experimental and Clinical Neuroscience
Expected to ship within 18 - 22 working days
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This is the third Proceedings book to arise from biennial conferen-
ces on the Trace Amines. Since our first meeting in 1983 in
Edmonton, Canada, progress has been brisk and, as will be seen from
the ensuing pages, it is now possible to include major
contributions from inverte- brate neurobiologists as well as
receptorologists. In the opening ses- sion we heard about the
distribution of the trace amines-now clear- ly a misnomer-in
insects and the pharmacological, receptor, and syn- aptic
characteristics of octopamine and tryptamine as well as the pos-
sibility of monoamines in general being targets for insecticide
discov- ery. In mammalian brain the distribution and
characterization of the tryptamine receptor has proceeded to the
point where two types have been described as well as novel agonists
and antagonists, and, for the first time, a binding site for
p-tyramine has been described. The com- bination of lesions and
pharmacological and metabolic manipulations now permits the mapping
of trace aminergic pathways, and the rap- idly accumulating
evidence from releasing drugs, in situ microdialy- sis,
iontophoresis, and second messenger systems lends credence to the
claim that the trace amines possess neuromodulatory functions.
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