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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Biomarkers of Human Aging (Hardcover, 1st ed. 2019)
Loot Price: R5,394
Discovery Miles 53 940
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Biomarkers of Human Aging (Hardcover, 1st ed. 2019)
Series: Healthy Ageing and Longevity, 10
Expected to ship within 12 - 17 working days
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This book collects and reviews, for the first time, a wide range of
advances in the area of human aging biomarkers. This accumulated
data allows researchers to assess the rate of aging processes in
various organs and systems, and to individually monitor the
effectiveness of therapies intended to slow aging. In an
introductory chapter, the editor defines biomarkers of aging as
molecular, cellular and physiological parameters that demonstrate
reproducible changes - quantitative or qualitative - with age. The
introduction recounts a study which aimed to create a universal
model of biological age, whose most predictive parameters were
albumin and alkaline phosphatase (indication liver function),
glucose (metabolic syndrome), erythrocytes (respiratory function)
and urea (renal function). The book goes on to describe DNA
methylation, known as the "epigenetic clock," as currently the most
comprehensive predictor of total mortality. It is also useful for
predicting mortality from cancer and cardiovascular diseases, and
for analyzing the effects of lifestyle factors including diet,
exercise, and education. Individual contributions draw additional
insight from research on genetics and epigenetic aging markers, and
immunosenescence and inflammaging markers. A concluding chapter
outlines the challenge of integrating of biological and clinical
markers of aging. Biomarkers of Human Aging is written for
professionals and practitioners engaged in the study of aging, and
will be useful to both advanced students and researchers.
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