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Gasotransmitters: Physiology and Pathophysiology (Paperback, 2012 ed.)
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Gasotransmitters: Physiology and Pathophysiology (Paperback, 2012 ed.)
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Since the epochal discovery of the radical and highly toxic gas
nitric oxide (NO) as a signaling molecule, two other no less toxic
gases - carbon monoxide (CO) and hydrogen sulfide (H2S) - have been
found to also be involved in a plethora of physiological and
pathophysiological functions. The gases termed gasotransmitters
play an increasingly important role in understanding how signalling
into and between cells is modulated and fine-tuned. The advent of
gasotransmitters has profoundly changed our way of thinking about
biosynthesis, liberation, storage and action mechanisms in cellular
signaling. In recent years an impressive amount of new data,
distributed throughout the existing literature, has been generated.
For this book the editors have recruited distinguished colleagues
in the field to summarize and review important biological,
pharmacological and medical functions and their implications, as
well as methods for the detection of gasotransmitters.
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