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Physics at the Biomolecular Interface - Fundamentals for Molecular Targeted Therapy (Paperback, Softcover reprint of the original 1st ed. 2016) Loot Price: R4,183
Discovery Miles 41 830
Physics at the Biomolecular Interface - Fundamentals for Molecular Targeted Therapy (Paperback, Softcover reprint of the...

Physics at the Biomolecular Interface - Fundamentals for Molecular Targeted Therapy (Paperback, Softcover reprint of the original 1st ed. 2016)

Ariel Fernandez

Series: Soft and Biological Matter

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Loot Price R4,183 Discovery Miles 41 830 | Repayment Terms: R392 pm x 12*

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This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics. The acknowledgment of how exquisitely the structure and dynamics of proteins and their aqueous environment are related attests to the overdue recognition that biomolecular phenomena cannot be effectively understood without dealing with interfacial behaviour. There is an urge to grasp how biologically relevant behaviour is shaped by the structuring of biomolecular interfaces and how interfacial tension affects the molecular events that take place in the cell. This book squarely addresses these needs from a physicist perspective. The book may serve as a monograph for practitioners and, alternatively, as an advanced textbook. Fruitful reading requires a background in physical chemistry and some basics in biophysics. The selected problems at the end of the chapters and the progression in conceptual difficulty make it a suitable textbook for a graduate level course or an elective course for seniors majoring in chemistry, physics, biomedical engineering or related disciplines.

General

Imprint: Springer International Publishing AG
Country of origin: Switzerland
Series: Soft and Biological Matter
Release date: June 2018
First published: 2016
Authors: Ariel Fernandez
Dimensions: 235 x 155 x 26mm (L x W x T)
Format: Paperback
Pages: 483
Edition: Softcover reprint of the original 1st ed. 2016
ISBN-13: 978-3-319-80900-7
Categories: Books > Medicine > Nursing & ancillary services > Pharmacy / dispensing
Books > Science & Mathematics > Biology, life sciences > Molecular biology
Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics
Books > Science & Mathematics > Chemistry > Physical chemistry > General
Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN: 3-319-80900-8
Barcode: 9783319809007

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