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Handbook of Drug Interactions - A Clinical and Forensic Guide (Paperback, Softcover reprint of the original 2nd ed. 2012)
Loot Price: R7,111
Discovery Miles 71 110
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Handbook of Drug Interactions - A Clinical and Forensic Guide (Paperback, Softcover reprint of the original 2nd ed. 2012)
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Adverse drug reactions and interactions are still a major headache
for healthcare professionals around the world. The US Food and Drug
Administration's database recorded almost 300,000 serious adverse
events in 2009 alone, of which 45,000 instances proved fatal. This
updated new edition of the indispensable guide to drug interactions
incorporates fresh research completed since the book's original
publication by Humana Press in 2004. Additions include a new
section on pharmacogenomics, a rapidly growing field that explores
the genetic basis for the variability of responses to drugs. This
new material reviews important polymorphisms in drug metabolizing
enzymes and applies the findings to forensic interpretation, using
case studies involving opiates as exemplars. Existing chapters from
the first edition have in most cases been updated and reworked to
reflect new data or incorporate better tables and diagrams, as well
as to include recent drugs and formulations. Recent references have
been inserted too. The handbook features extra material on illicit
drug use, with a new chapter tackling the subject that covers
cocaine, amphetamines and cannabis, among others. The section on
the central nervous system also deals with a number of drugs that
are abused illicitly, such as benzodiazepines, opiates
flunitrazepam and GHB, while so-called 'social' drugs such as
alcohol and nicotine are still discussed in the book's section on
environmental and social pharmacology. Focusing as before on
detailed explanation and incorporating both pharmacokinetic and
pharmacodynamic drug interactions, this book will continue to be a
lodestar for health and forensic professionals as well as students.
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