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Early Nutrition and Lifestyle Factors - Effects on First Trimester Placenta (Hardcover, 1st ed. 2016)
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Early Nutrition and Lifestyle Factors - Effects on First Trimester Placenta (Hardcover, 1st ed. 2016)
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This book highlights the impact of nutrients on early placentation
processes and their relevance for fetal growth and pregnancy
outcome. The role of maternal nutrition on fetal growth and
development has been evidenced in many epidemiological studies that
included infamous Dutch famine, Helsinki Birth cohort and others.
Fetal programming hypothesis states that the nutritional and other
environmental conditions under which an individual develops from
pre-conception to birth has a major impact on the future health of
the newborn child. The developmental environment of the fetus is
primarily dependent on two major factors that are maternal
nutritional state (excess/low/imbalance) and placental function.
Placentation is characterized by the extensive remodeling of the
maternal uterine vasculature producing low-resistance blood vessels
that facilitate the exchange of nutrients and wastes between the
mother and the fetus. Cellular and molecular mechanisms involved in
human placental blood vessel formation, which are now well
established, are discussed.
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