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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Systems Biology - Constraint-based Reconstruction and Analysis (Hardcover, 2 Rev Ed)
Loot Price: R2,129
Discovery Miles 21 290
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Systems Biology - Constraint-based Reconstruction and Analysis (Hardcover, 2 Rev Ed)
Expected to ship within 10 - 15 working days
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Recent technological advances have enabled comprehensive
determination of the molecular composition of living cells. The
chemical interactions between many of these molecules are known,
giving rise to genome-scale reconstructed biochemical reaction
networks underlying cellular functions. Mathematical descriptions
of the totality of these chemical interactions lead to genome-scale
models that allow the computation of physiological functions.
Reflecting these recent developments, this textbook explains how
such quantitative and computable genotype-phenotype relationships
are built using a genome-wide basis of information about the gene
portfolio of a target organism. It describes how biological
knowledge is assembled to reconstruct biochemical reaction
networks, the formulation of computational models of biological
functions, and how these models can be used to address key
biological questions and enable predictive biology. Developed
through extensive classroom use, the book is designed to provide
students with a solid conceptual framework and an invaluable set of
modeling tools and computational approaches.
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