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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA
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Regulatory RNAs - Basics, Methods and Applications (Hardcover, 2012)
Loot Price: R5,680
Discovery Miles 56 800
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Regulatory RNAs - Basics, Methods and Applications (Hardcover, 2012)
Expected to ship within 10 - 15 working days
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Recent progress in high-throughput technologies and genome wide
transcriptome studies have lead to a significant scientific
milestone of discovering non-coding RNAs (ncRNAs) which spans
through a major portion of the genome. These RNAs most often act as
riboregulators, and actively participate in the regulation of
important cellular functions at the transcriptional and/or
post-transcriptional levels rather than simply being an
intermediated messenger between DNA and proteins. As the
appreciation for the importance of ncRNAs continues to emerge, it
is also increasingly clear that these play critical roles in gene
regulatory processes during development and differentiation.
Further, regulatory RNAs are useful biomarkers for diagnosis of
diseases. Hence these RNA regulators are essential to the
development of therapeutics. This book on "Regulatory RNAs" offers
a comprehensive view on our current understanding of these
regulatory RNAs viz. siRNA, miRNA, piRNA, snoRNA, long non-coding
RNA, small RNA etc. It addresses both the biogenesis and mechanism
of action of regulatory RNAs with a primary focus on their
annotation, experimental methodologies (microarray, next-gen
sequencing etc.) for their discovery, computational tools for their
prediction, and above all, applications of these revolutionary
regulatory molecules in understanding biological systems and
diseases, including therapeutics. This comprehensive volume is
intended for readers with research or teaching interests in ncRNA
biology and will provide a major information resource on current
research in the fast-moving fields of RNA and gene expression
regulation. Cutting-edge and concise, "Regulatory RNAs: Basics,
Methods and Applications" promises to support vital research in the
field of regulatory RNAs, ever-continuing to grow rapidly and gain
increasing importance in basic and translational biology.
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