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Genetics of Cellular, Individual, Family, and Population Variability (Hardcover)
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Genetics of Cellular, Individual, Family, and Population Variability (Hardcover)
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The objective of this book is to review the impact of genetic
variation on risk of human disease at the different major levels of
organization: cells, individuals, families, and populations. The
volume begins with a discussion of sources and rates of mutation
which ultimately give rise to the vast amount of extant genetic
variation. This is followed by presentations of current
understanding of how genetic variation is maintained within and
among populations. The volume ends with discussions of the
implications of such variation for understanding the evolution of
our species. This collection gives an unusually broad treatment of
the subject, with chapters from some of the leading workers in the
field. James Neel's chapter on human consanguinity effects and M.
Otake's on the genetic effects of radiation associated with the
dropping of the Hiroshima and Nagasaki atomic bombs should be
singled out for special emphasis. As an up-to-date overview of
ongoing research, this work will be of interest to a wide range of
workers in the fields of human population genetics, evolution, and
epidemiology.
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