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Books > Medicine > Clinical & internal medicine > Haematology
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Hematopoietic Stem Cells - Animal Models and Human Transplantation (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R2,646
Discovery Miles 26 460
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Hematopoietic Stem Cells - Animal Models and Human Transplantation (Paperback, Softcover reprint of the original 1st ed. 1992)
Series: Current Topics in Microbiology and Immunology, 177
Expected to ship within 10 - 17 working days
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The idea for this volume was conceived during a discussion in the
hallway at a conference in early 1990. "What is the best way to
detect and define pluripotent hematopoietic stem cells?" was the
question posed by Dr. Fritz Melchers. After discussing the pros and
cons of the available assays for quite some time, it became
apparent that this topic required a wider expertise and merited a
larger forum. Thus, we decided to extend the discussion and to
compile the results in this volume. Much to our delight. many of
the pioneers of recent experimental and theoretical developments in
stem cell research agreed to contribute their expertise to answer
the question. These authors review both past findings and present
insights, thus providing an overview of the evolution that has been
and is occurring in the field of stem cell research. In the light
of recent trailblazing developments in both experimental models and
in clinical application it is indeed time to reevaluate our
knowledge about stem cells. Trans plantation of hematopoietic stem
cells has become more and more prevalent as a curative therapy in a
variety of acquired and genetic diseases, including cancer,
radiation accident, as an agent for gene therapy, and perhaps even
as treatment for autoimmune diseases. Stem cells are now derived
not only from bone marrow but also from peripheral blood, cord
blood, and fetal liver, greatly increasing their availability for
human transplantation and in some cases (fetal tissues)
obliterating the need to match donors and hosts."
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