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Introduction to Modeling in Physiology and Medicine (Paperback, 2nd edition)
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Introduction to Modeling in Physiology and Medicine (Paperback, 2nd edition)
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Introduction to Modeling in Physiology and Medicine, Second
Edition, develops a clear understanding of the fundamental
principles of good modeling methodology. Sections show how to
create valid mathematical models that are fit for a range of
purposes. These models are supported by detailed explanation,
extensive case studies, examples and applications. This updated
edition includes clearer guidance on the mathematical prerequisites
needed to achieve the maximum benefit from the material, a greater
detail regarding basic approaches to modeling, and discussions on
non-linear and stochastic modeling. The range of case study
material has been substantially extended, with examples drawn from
recent research experience. Key examples include a cellular model
of insulin secretion and its extension to the whole-body level, a
model of insulin action during a meal/oral glucose tolerance test,
a large-scale simulation model of type 1 diabetes and its use in in
silico clinical trials and drug trials.
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