This volume sets out to consider a range of cardiac diseases for
which drugs may play a therapeutic role by virtue of their effects
on aspects of the immune system. The book reviews diseases of the
heart which may involve an immunopharmacological component, and
methods and techniques for the study of physiological and
biochemical functions in the heart. An important focus is the
immunopharmacology of the coronary vascular endothelium and the
role of cellular and biochemical components of the immune system in
the pathogenesis of atherosclerosis. The content also includes a
review of the use of immunologically relevant agents in the setting
of cardiac transplantation from aclinical perspective.
Immunotherapy has a definite role to play in cardiology to a
greater or lesser extent than other forms of intervention,
depending on the type of cardiac disease. Immunopharmacology of the
Heart aims to identify and clarify this role and points to
potential developments of the future. Immunopharmacology of the
Heart is a volume for the SYSTEMS theme of The Handbook of
Pharmacology. In common with all other volumes it contains
standardized illustrations and terms/abbreviations (glossaries of
illustrations and terms published at the back of the volume). Other
topics covered include: Leukocytes and their role in ischaemic
heart disease. Complement activation. Sudden cardiac death. The
stunned myocardium and reperfusion injury.
General
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