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Hox Modules in Evolution and Development (Hardcover)
Loot Price: R2,681
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Hox Modules in Evolution and Development (Hardcover)
Series: Evolutionary Cell Biology
Expected to ship within 12 - 17 working days
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Few, if any, genes have had the same level of impact on the field
of evolutionary-developmental biology (evo-devo) as the Hox genes.
These genes are renowned for their roles in patterning the body
plans and development of the animal kingdom. This is complemented
by the distinctive organisation of these genes in the genome, with
them frequently being found as clusters in which gene position is
linked to when and where the individual genes are expressed,
particularly during embryogenesis. This book provides the latest
overviews of Hox gene organisation and function for major clades of
animals from across the animal kingdom. With the rapidly increasing
availability of high-quality whole genome sequences from an
ever-expanding range of species, it is becoming increasingly
evident that there is great diversity in the organisation of Hox
genes. These great strides in genome sequencing are wedded to
important developments in our ability to detect expression and
disrupt gene function in species that are not traditionally
genetically-amenable animals. These technical developments are
integrated with wide taxon-sampling in this volume to provide new
perspectives on the roles of Hox genes in understanding fundamental
issues such as embryo patterning, mechanisms of gene regulation,
homology, evolvability, evolutionary novelties, phylogeny, the role
of gene and genome duplications in evolution, and ancestral states
for major clades of animals. Key features Integrative overviews
from major animal groups including, arthropods, vertebrates,
echinoderms, mollusks and other spiralians. Perspectives gleaned
from the latest genome sequence and gene expression data.
Individual chapters written by world-leading experts in Hox genes
and evo-devo in each animal group. Related Titles Scholtz, G., ed.
Evolutionary Developmental Biology of Crustacea (ISBN
978-9-0580-9637-1) Mattick, J. & P. Amaral. RNA, The Epicenter
of Genetic Information (ISBN 978-0-3675-6778-1) Bard, J. Evolution:
The Origins and Mechanisms of Diversity (ISBN 978-0-3673-5701-6)
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