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Xenotransplantation - The Transplantation of Organs and Tissues Between Species (Paperback, 2nd ed. 1997. Softcover reprint of the original 2nd ed. 1997)
Loot Price: R4,402
Discovery Miles 44 020
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Xenotransplantation - The Transplantation of Organs and Tissues Between Species (Paperback, 2nd ed. 1997. Softcover reprint of the original 2nd ed. 1997)
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This is a time ofexcitement and progress in the field
ofxenotransplantation. The work described in this book traces the
development of the science of cross-spe cies transplantation,
summarizes the current state ofour knowledge, and focuses on
approaches directed toward future clinical application. The
important question is not whether xenotransplantation will succeed,
but rather how and under what circumstances xenografts will provide
predictable enough results to warrant clinical application. The
fact that the best results to date in clinical xenografting were
achieved over three decades ago should not be a matter of
discouragement, but rather a stimulus to apply new approaches to
this area of work. The shortage of human organs for transplantation
is cited frequently as the driving force behind the increased
interest in xenotransplantation. This shortage is an undeniable
fact, but there are additional potential advantages of xenotrans
plantation, such as the ability to schedule replacement surgery on
an elective basis and the modification of animals, organs, and
tissues to improve acceptabil ity in the human host. The advances
in the basic science ofxenotransplantation outlined in this book
give hope that the immunologic barriers to xenotransplantation will
be overcome and that transplanted organs and tissues will succeed
consistently in humans. However, if our experience with human
allografts provides an analogy, we may anticipate that clinical
progress in xenografts will be plagued by failures and rewarded by
successes, often without a complete understanding of the mechan
isms involved."
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