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The Hereditary Basis of Childhood Cancer (Hardcover, 1st ed. 2021)
Loot Price: R7,354
Discovery Miles 73 540
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The Hereditary Basis of Childhood Cancer (Hardcover, 1st ed. 2021)
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This volume elaborates on the research and clinical implications of
the hereditary and molecular basis of childhood cancers. The focus
of the 'disease-related' chapters of the book is to integrate what
is known about the molecular basis of that particular clinical
entity (or group of related entities) with the clinical
manifestations, to relate the relationship of the molecular
oncologic pathways with relevant developmental or non-human species
biology in order to better understand the complexity of these
systems. The resulting clinical implications of understanding this
biology are elaborated on. Chapters 13-16 discuss the broader
psychosocial, ethical and genetic counseling issues that arise and
that are so critical to translating the knowledge gained from
advances in molecular genetics into the clinic. Chapter 12 in
particular provides a unique perspective of the application of this
knowledge in less-developed nations where 'modern' technologies may
not be readily available, but where the clinical manifestations of
these disorders are prevalent.
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