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Molecular Aspects of Chemotherapy - Proceedings of the Third International Symposium on Molecular Aspects of Chemotherapy Gdansk, Poland June 19-21, 1991 (Paperback, Softcover reprint of the original 1st ed. 1992)
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Molecular Aspects of Chemotherapy - Proceedings of the Third International Symposium on Molecular Aspects of Chemotherapy Gdansk, Poland June 19-21, 1991 (Paperback, Softcover reprint of the original 1st ed. 1992)
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While serendipity and random screening continue to fulfil a
significant role in the search for new drugs, current remarkable
advances in molecular biology and genetics are dictating to a
profound extent the approaches employed in their development.
Increasing attention is being devoted to investigations of the
mechanisms of action of existing drugs, and the sources of
undesired side effects, at the molecular level. The information so
derived is now extensively applied, with the aid of broad inter
disciplinary approaches, both theoretical and experimental, to
improvements in existing drugs, and the rational design of new
ones. The foregoing comprised the subject matter of the 3rd Inter
national Symposium on "Molecular Aspects of Chemotherapy," under
the auspices of the International Society of Chemotherapy, and
organized by the Committee on Drug Research, Polish Academy of
Sciences, and the Department of Biotechnology and Biochemistry,
Technical University of Gdansk. This volume includes the texts of
the review lectures presented by invited participants on up-to-date
achievements, and future perspectives, in molecular mechanisms of
inhibition of cellular functions and metabolism, with emphasis on
the design and mechanisms of action of chemotherapeutic agents for
treatment of bacterial, neoplastic, viral and parasitic diseases.
From the Contents, it will be seen that the range of disciplines
represented was a broad one, including theoretical and experimental
chemists, physicists, molecular biologists, biochemists,
enzymologists, virologists, tumour biologists. Plenary sessions
were supple mented by several poster sessions."
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