Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease (Hardcover, 2015 ed.)

Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family. Receptor Tyrosine Kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases. And over the last decade they have become the Number 1 targets of cancer drugs. To be able to conduct fundamental research or to attempt to develop pharmacological agents able to enhance or intercept them, it is essential first to understand the evolutionary origin of the 58 RTKs and their roles in invertebrates and in humans, as well as downstream signaling pathways. The assembly of chapters is written by experts and underscores commonalities between and among the RTKs. It is an ideal companion volume to The Receptor Tyrosine Kinase: Families and Subfamilies, which proceeds, family by family through all of the specific subfamilies of RTKs, along with their unique landmarks.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Release date:	December 2014
First published:	2015
Editors:	Deric L. Wheeler • Yosef Yarden
Dimensions:	235 x 155 x 25mm (L x W x T)
Format:	Hardcover
Pages:	440
Edition:	2015 ed.
ISBN-13:	978-1-4939-2052-5
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4939-2052-9
Barcode:	9781493920525

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