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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Angiotensin Protocols (Hardcover, 2001 ed.)
Loot Price: R4,154
Discovery Miles 41 540
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Angiotensin Protocols (Hardcover, 2001 ed.)
Series: Methods in Molecular Medicine, 51
Expected to ship within 10 - 17 working days
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A qualitative leap in the understanding of cardiovascular and n-
ral regulation by the renin-angiotensin system, and of the role of
this s- tem in tissue damage, has occurred as a result of the many
recent advances in molecular genetic techniques. The cloning of the
genes for the components of the renin-angiotensin system, the
design of specific angiotensin receptor ligands, and the use of
embryonic gene targeting te- niques for the creation of mutant
strains have established that the renin- angiotensin system is
important in blood pressure regulation, ion and fluid homeostasis,
and tissue growth and remodeling Further investigation of the
mechanisms by which this system p- ticipates in cardiovascular
regulation may shed some light on the pat- genesis of several
cardiovascular diseases, e. g. , hypertension, congestive heart
failure, and chronic renal failure. Despite the promise of this
system as a target for therapeutic interventions for these
diseases, there are great challenges in the integration of the
attempts to close the gap between the traditional literature of
medicine and the explosion of information from the new
technologies. This book's title, Angiotensin Protocols, reflects
the authors' strong efforts to translate expert knowledge into
easy-to-follow practice. The book opens with introductory chapters,
and each specialty section provides detailed methods covering a
wide variety of techniques, ranging from genetic manipulation of
targeted genes to functional studies of the renin- angiotensin
system.
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