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Diabetic Renal-Retinal Syndrome - 21st Century Management Now (Paperback, Softcover reprint of the original 1st ed. 1998)
Loot Price: R4,345
Discovery Miles 43 450
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Diabetic Renal-Retinal Syndrome - 21st Century Management Now (Paperback, Softcover reprint of the original 1st ed. 1998)
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After a decade or longer, approximately one-third of individuals
with either type 1 or type 2 diabetes commence a downhill course in
which decreasing renal function and failing vision define a
Renal-Retinal Syndrome, dominating all aspects of life and
presaging early death. Only a generation ago, survival after onset
of end-stage renal disease (ESRD) in diabetes was limited because
rehabilitation was preempted by blindness, limb amputation, stroke,
and heart disease. By 1998, however, team management has improved
the outlook, with preserved sight and return to work and home
responsibilities, usually for a decade or longer, following kidney
transplantation and laser photocoagulation. Recognition of the
critical requirement for blood pressure regulation and metabolic
control are central themes in management. In this unique book, the
accomplishments of ophthalmologists, nephrologists, diabetologists,
transplant surgeons, and basic scientists are blended into a
strategic approach that may be readily applied by all those caring
for diabetic patients. Each of twenty-one presentations suitable
for primary care physicians, as well as for subspecialists
concerned with macrovascular and microvascular complications of
diabetes, is placed in perspective by an introductory editorial
analysis. Promising near-term innovative therapies, including
insertion of genetically engineered beta cells or polymer-coated
islets of Langerhans, interdiction of kinins that promote retinal
angiogenesis, and prevention of synthesis of advanced glycosylated
endproducts (AGEs), are presented in detail. While comprehensive
care of diabetic patients reflects multiple incremental advances
that in sum afford major benefit, this text envisions further
remarkable changes likely to suppress and possibly entirely prevent
the Diabetic Renal-Retinal Syndrome.
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