Now considered an organ with defensive and metabolic capabilities,
the intestinal microbiota plays a major role in the local host
immune system development and education. It contributes to the
generation of a homeostatic balance characterized by the capacity
to react against pathogens while remaining hyperresponsive/tolerant
against commensals. This homeostatic response depends on bacteria
and bacterial product sensing by innate immune cells and their
molecular asset at the intestinal mucosa. This book captures the
enormous progress that has been accomplished in this field in
recent years.
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