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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy (Hardcover, 1st ed. 2016)
Loot Price: R3,180
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Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy (Hardcover, 1st ed. 2016)
Series: Resistance to Targeted Anti-Cancer Therapeutics, 9
Expected to ship within 12 - 17 working days
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This volume focuses on recent advances in understanding T cells as
key players in antitumor immune responses, and as a result T
cell-based immunotherapy is starting to transform the treatment of
advanced cancers. However, despite recent successes, many patients
with cancer fail to respond to these treatments. Defective
migration of T cells into and within tumors is considered as an
important resistance mechanism to cancer immunotherapy.The volume
includes three sections. The first section covers general knowledge
about T cell trafficking during a normal immune response but also
during tumor development. The second section provides an in-depth
description of the different obstacles that prevent T cells from
migrating and contacting tumor cells. The third section explores
therapeutic strategies to improve trafficking of T cells into
tumors and, thus, to enhance the effectiveness of cancer
immunotherapy.
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