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Protein Structure and Protein Engineering (Paperback, Softcover reprint of the original 1st ed. 1988)
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Discovery Miles 23 820
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Protein Structure and Protein Engineering (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: Colloquium der Gesellschaft fur Biologische Chemie in Mosbach Baden, 39
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Protein engineering has had considerable impact on basic and
applied research in biochemistry and molecular biology. It is
already in use as a tool in molecular biology, but it is beginning
to strongly influence the planning of experiments in biology
everywhere, and, with even fur ther-reaching consequences, the
appointment politics in research in stitutions and industries.
Protein engineering, perhaps more than any other methods of protein
analysis and peptide synthesis, has shown that proteins are organic
molecules governed by the universal laws of chemistry and physics.
How ever, as was the case with other new powerful methods and
techniques, protein engineering tempts to an exploration of its
limitations and thus generates more questions than it answers. The
39th Mosbacher Colloquium on Protein Structure and Protein Engi
neering is not the first conference on this topic and it will not
be the last. The important issues are obviously techniques of
protein en gineering, examples of application, and the basic
framework of protein structure and stability within which
reasonable experiments can be de signed; conversely also, what we
can learn about protein structure, dynamics, and folding from such
experiments. Experiments in this direc tion aim at elucidating the
folding code in the long run, but help to exploit the role of
individual amino acid residues in catalysis, pro tein stability,
and binding specificity in selected proteins now."
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