"Apoptosome" is the first book that presents a concise synthesis
of recent developments in the understanding of how the activation
of the cell death cascade is handled by a cytosolic signalling
platform known as the apoptosome.
The book also discusses how insights into the regulation of
apoptosome may be exploited for designing new drugs aimed at
interfere with a plethora of pathogenetic processes involved in
human diseases.
The authors emphasize novel translational approaches that are
rapidly moving from the laboratory bench top to the patient's
bedside for the future treatment of diseases associated with
apoptosis.
This book will be a valuable resource for researchers
investigating the role of apoptosome-dependent cell death in cancer
and other diseases, for researchers investigating the molecular
mechanism of chemotherapeutic agents and drug-resistance and for
physicians using chemotherapeutic agents. Additionally, this book
will be an important educational source for PhD students and MD
students specializing in molecular and cell biology, and to anybody
interested in science, medicine, as well as in recent developments
of the ideas and concepts of the molecular biology of programmed
cell death.
General
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