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Chromosomal Translocations and Oncogenic Transcription Factors (Paperback, Softcover reprint of the original 1st ed. 1997) Loot Price: R2,756
Discovery Miles 27 560
Repayment Terms: R258 pm x 12*
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Chromosomal Translocations and Oncogenic Transcription Factors (Paperback, Softcover reprint of the original 1st ed. 1997):...

Chromosomal Translocations and Oncogenic Transcription Factors (Paperback, Softcover reprint of the original 1st ed. 1997)

Frank J. III Rauscher, Peter K. Vogt

Series: Current Topics in Microbiology and Immunology, 220

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Loot Price R2,756 Discovery Miles 27 560 | Repayment Terms: R258 pm x 12*

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Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. The key players in these processes are sequence-specific DNA binding transcription factor proteins which coordinate programs of gene expression in the nucleus. The articles in this volume document the myriad of genetic and biochemical alterations sustained by human proto-oncogenic transcription factors which result in diverse neoplastic processes. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type. The book provides inspiration for exploiting these tumor-specific alterations as diagnostic, prognostic tools, or as selective therapeutic targets.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Current Topics in Microbiology and Immunology, 220
Release date: October 2011
First published: 1997
Editors: Frank J. III Rauscher • Peter K. Vogt
Dimensions: 235 x 155 x 9mm (L x W x T)
Format: Paperback
Pages: 166
Edition: Softcover reprint of the original 1st ed. 1997
ISBN-13: 978-3-642-64424-5
Categories: Books > Medicine > General issues > Medical equipment & techniques > Medical research
Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN: 3-642-64424-4
Barcode: 9783642644245

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