|
Books > Medicine > Clinical & internal medicine > Paediatric medicine
|
Buy Now
Peroxisomal Disorders and Regulation of Genes (Paperback, Softcover reprint of the original 1st ed. 2003)
Loot Price: R4,081
Discovery Miles 40 810
|
|
|
Peroxisomal Disorders and Regulation of Genes (Paperback, Softcover reprint of the original 1st ed. 2003)
Series: Advances in Experimental Medicine and Biology, 544
Expected to ship within 10 - 17 working days
|
In most peroxisomal disorders the nervous system is severely
affected which explains the clinical and community burden they
represent. This is the first book to focus not only on the
mutations causing these inherited illnesses, but also on mechanisms
that regulate, suppress or enhance expression of genes and their
products (enzymes). Indeed since the success and completion of the
Human Genome Project all genes (coding DNA sequences) are known.
However, of many, their function, and the role of the gene product
has not been determined. An example is X-linked
adrenoleukodystrophy, the most frequent peroxisomal disorder.
Children are born healthy, but in more than 1 out of 3,
demyelination of the brain starts unpredictably and they die in a
vegetative state. The gene mutated in most families has been known
for 10 years; but the true role of the encoded protein, ALDp, is
still speculative; and within the same family, very severe and
asymptomatic clinical histories co-exist, unexplained by the
mutation.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
