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Principles of Cancer Genetics (Hardcover, 3rd ed. 2022)
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Principles of Cancer Genetics (Hardcover, 3rd ed. 2022)
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This popular textbook, now in its third edition, provides a
theoretical framework for understanding why cancers arise, how they
develop and how they can be treated. Particular attention is
devoted to the origins of cancer and the application of
evolutionary theory to explain how mutant cell populations tend to
expand and spread. Focused on the genes and signaling pathways
involved in the most common tumors, Principles of Cancer Genetics
is a highly readable account that will be of interest to anyone who
would like to attain a basic understanding of cancer biology.
Students who have completed introductory coursework in genetics,
biology and biochemistry, medical students and medical house staff
will find this book to be a useful starting point toward mastery of
this complex but fascinating topic. This updated edition delves
into the critical interactions between growing tumors and the
immune system, and introduces the concepts of T cell activation,
immunoediting and immune evasion. Novel strategies for cancer
diagnosis and prognosis, including new roles for next-generation
sequencing and liquid biopsies, as well as established and emerging
therapeutic modalities are now described in detail. For laypersons,
students and researchers in other fields with a general interest in
cancer, this book provides an accessible overview, enriched with
many easy-to-understand illustrations. For advanced students
considering future study in the field of oncology and cancer
research, this concise book is a useful guide to the basic
principles that underlie our understanding of cancer.
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