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Treatment of Asthma: The long-acting beta-2-agonists (Paperback)
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Treatment of Asthma: The long-acting beta-2-agonists (Paperback)
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The traditional Vienna Asthma Forum was held in early June 1996 and
th was the 6 in a biennial mode within 10 years. This time it was
dedicated to the long-acting beta-2-agonists, which were registered
(or just about to be) in most European countries. The introduction
of this therapeutic principle into routine praxis of asthma therapy
was so successful that a closer view on the subject from a
scientific point was warranted. Salmeterol, shortly afterwards
formo- terol are the drugs available for the inhalative route,
while bambuterol serves as an oral agent. The scientists
particularly involved in the design and pharma- cokinetics of these
drugs were invited, and we were lucky that Malcolm Johnson (Glaxo),
Leif Svensson (Astra) and Gary Anderson (Ciba- Geigy) delivered
fascinating contributions. However, drug therapy of this kind can
only be effective if based on a thorough understanding of the
molecular biology of cells and receptors, which was superbly
covered by Sheila Collins (Durham) and Ian M. Adcock (London). The
pediatric indications for beta-2-agonists were commented by Manfred
G6tz (Vienna), and a large spectrum of clinical studies, reported
by G. Boyd (Glasgow), A.P. Greening (Edinburgh), M.
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