As cancer research increasingly becomes an applied science,
academic and biotech researchers interested in general principles
must think more about how their efforts translate into the clinical
arena. At the same time, researchers on the industrial side stand
to gain from a better understanding of the latest strategies for
target and lead drug discovery. This way the great promise of new
approaches to cancer drug development-preventions and treatments
that will be less toxic and more effective than current drugs
through targeting specific molecular features of aberrant cells-can
finally be fulfilled.
Molecular Cancer Therapeutics: Strategies for Drug Discovery and
Development offers an up-to-date overview of the different phases
of drug discovery and preclinical development of new experimental
cancer principles. In tying together the diverse set of disciplines
and methods involved in these pursuits, the text covers:
- Discovery and validation of drug targets
- Drug screening
- Animal models
- Preclinical testing
- Pharmacology issues
- Clinical concerns
- Intellectual property issues
Directed to a broad audience of students and professionals in
academia and industry, Molecular Cancer Therapeutics provides a
comprehensive summary of state-of-the-art strategies for
identifying drug targets and developing lead inhibitors. With its
coverage of target validation, drug screening, and
pharmacokinetics, it is an invaluable reference for those working
in oncology as well as the broad range of disciplines concerned
with drug discovery and development.
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