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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Voltage-Gated Calcium Channels (Hardcover, 2005 ed.)
Loot Price: R5,838
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Voltage-Gated Calcium Channels (Hardcover, 2005 ed.)
Series: Molecular Biology Intelligence Unit
Expected to ship within 10 - 15 working days
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oltage-gated calcium channels are essential mediators of a range of
physiological functions, including the communication between nerve
Vcells, the regulation of heart beat, muscle contraction, and
secretion of hormones such as insulin. Consequently, these channels
are critical phar macological targets in the treatment of a variety
of disorders, such as epi lepsy, hypertension, and pain.
Voltage-gated calcium channels have there fore been subject to
intense study by numerous investigators over the past few decades,
and an immense body of work has accumulated. In this book, we
provide the first comprehensive overview of our current state of
knowl edge concerning this exciting field of research. Leading off
with a general review of calcium signaling and techniques to
measure calcium channel ac tivity, the book delves into a
provocative overview of the history of the cal cium channel field,
contributed by one of the key pioneers in the field. Dr. Richard
Tsien. This is followed by an in depth review of the biochemical
and molecular biological characterization of calcium channel genes
by Drs. Catterall and Snutch whose research has resulted in major
advances in the calcium channel field. A number of chapters are
dedicated towards various aspects of calcium channel structure and
function, including channel gat ing, permeation, modulation and
interactions with members of the exo- totic machinery-contributed
by both established leaders and rising stars in the field."
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