Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Biomarkers in Breast Cancer (Hardcover, 2006 ed.)
Loot Price: R5,471
Discovery Miles 54 710
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Biomarkers in Breast Cancer (Hardcover, 2006 ed.)
Series: Cancer Drug Discovery and Development
Expected to ship within 10 - 15 working days
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Expert laboratory and clinical researchers from around the world
review how to design and evaluate studies of tumor markers and
examine their use in breast cancer patients. The authors cover both
the major advances in sophisticated molecular methods and the
state-of-the-art in conventional prognostic and predictive
indicators. Among the topics discussed are the relevance of
rigorous study design and guidelines for the validation studies of
new biomarkers, gene expression profiling by tissue microarrays,
adjuvant systemic therapy, and the use of estrogen, progesterone,
and epidermal growth factor receptors as both prognostic and
predictive indicators. Highlights include the evaluation of HER2
and EGFR family members, of p53, and of UPA/PAI-1; the detection of
rare cells in blood and marrow; and the detection and analysis of
soluble, circulating markers.
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