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Vaccine Design - The Role of Cytokine Networks (Hardcover, 1998 ed.)
Loot Price: R4,331
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Vaccine Design - The Role of Cytokine Networks (Hardcover, 1998 ed.)
Series: NATO Science Series A:, 293
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During the last decade or so vaccine development has been
facilitated by rapid ad- vances in the molecular and cell biology
ofthe immune system. This has laid the foundations of a new
generation of vaccines exemplified by subunit vaccines produced
through gene cloning and by synthetic peptides mimicking small
regions ofproteins on the outer coat ofvi- ruses. However, as
subunit and peptide vaccines are only weakly or non-immunogenic,
there is areal need for strategies to improve their potency. This
book contains the proceedings of the 5th NATO Advanced Studies
Institute (ASI), "Vaccine Design: The Role of Cytokine Networks,"
held at Cape Sounion Beach, Greece, during 24 June-5 July 1996 and
deals in depth with the role ofbasic immunology in the regulation
of immunity and vaccine design. Special emphasis is given to the
use of cyto- kines in conjuction with vaccines with the aim
ofimproving their potency or the use ofvac- cines designed to
improve cytokine production. We express our appreciation to Dr.
J.-L. Virelizier and Dr. G. Kollias for their cooperation in
planning the ASI and to Mrs. Concha Perring for her excellent
production ofthe manuscripts. The ASI was held under the sponsor-
ship of NATO Scientific Affairs Division and generously
co-sponsored by SmithKline Beecham Pharmaceuticals (Philadelphia).
Financial assistance was also provided by Connaught Laboratories
Ltd. (Ontario), Pasteur Merieux (Marcy I 'Etoile), Biochine
(Siena), Help SA (Athens), and Avanti Polar Lipids Inc.
(Birmingham, USA).
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