Expanding from the classic use of immunosuppressants in
transplantation and rejection, this current overview highlights
their new roles in clinical medicine. Immunosuppressants are at the
forefront of new treatment modalities. Individual chapters focus on
their use not only in prevention or treatment of transplant
rejection, but also on their use in immune-complex and autoimmune
diseases, including rheumatoid arthritis; on combination therapies
to achieve synergy in immunosuppression; on new drugs, low
molecular weight chemicals, the use of antibodies and gene therapy;
on immunological tolerance to prevent or inhibit transplant
rejection; and how data derived from transplant studies can be
applied to other avenues of immunosuppression. Clinicians and
researchers will appreciate the scope of the work and the
presentation of new approaches in the rapidly developing field of
immunosuppression.
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