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Hepatocellular Carcinoma - An Atlas of Its Pathology (Paperback, Softcover reprint of the original 1st ed. 1987)
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Hepatocellular Carcinoma - An Atlas of Its Pathology (Paperback, Softcover reprint of the original 1st ed. 1987)
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Hepatocellular carcinoma is one of the most common fatal malignan
cies of mankind. Up to a few decades ago it was looked upon as a
cancer which aroused mainly academic concern but relatively little
clinical interest, because its therapy and prognosis had a most un
favorable outlook. Indeed, it was mostly recognized only at
autopsy. Recently this pessimism has radically changed and is
disappearing to a rapidly accelerating degree. Many of the
scientific contributions at this change in outlook are the result
of research in the Far East, first, Japan and then gradually
extending to its neighbors. The introduction of experimental
hepatocarcinogens by Yoshida more than 50 years ago may have been
one of the first important steps. Hepatocellular car cinoma shows a
characteristic geographical distribution. With the highest
incidence in China, Taiwan, Southeast Asia and sub-Saharan Africa,
followed by southern and eastern Europe, while generally the
incidence is rather low in western and northern Europe and North
and South America.
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