Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing (Paperback, 2015 ed.)

Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion.

General

Imprint:	Springer Spektrum
Country of origin:	Germany
Release date:	June 2015
First published:	2015
Authors:	Hamed Alborzinia
Dimensions:	210 x 148 x 10mm (L x W x T)
Format:	Paperback
Pages:	153
Edition:	2015 ed.
ISBN-13:	978-3-658-10160-2
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	3-658-10160-1
Barcode:	9783658101602

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